2-(Difluoromethyl)-1,4-difluorobenzene CAS 195886-79-4
| CAS No. | 195886-79-4 |
| Molecular Formula | C7H4F4 |
| Molecular Weight | 164.10 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Owing to fluorine substitution, an aromatic ring system, 2-(Difluoromethyl)-1,4-difluorobenzene is typically off-white to pale yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 164.10 g/mol — guide the selection of appropriate sample preparation and analytical techniques. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
CATO supplies 2-(Difluoromethyl)-1,4-difluorobenzene (CAS 195886-79-4), a certified reference material (molecular formula C7H4F4, MW 164.10 g/mol) for analytical method development and quality control.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
As a certified reference material (CRM), 2-(Difluoromethyl)-1,4-difluorobenzene meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C7H4F4 |
| Molecular Weight | 164.10 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO |
| Stability | May oxidize slowly on prolonged air exposure |
| Degree of Unsaturation (DBE) | 4.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2012 |
| Halogen Content | F-containing |
Related Difluoromethyl Standards
- 1-(Difluoromethyl)-3,5-difluorobenzene (CAS 1208077-70-6)
- 1-(Difluoromethyl)-2,3-difluorobenzene (CAS 1214349-96-8)
- 4-(Difluoromethyl)-1,2-difluorobenzene (CAS 1214379-64-2)
- 1-(Difluoromethyl)-2,4-difluorobenzene (CAS 845866-84-4)
- 2-(Difluoromethyl)-1,3-difluorobenzene (CAS 91624-89-4)
- 4-(Difluoromethyl)dihydro-2H-pyran-2,6(3H)-dione (CAS 1706461-52-0)
- 1-(Difluoromethyl)-3-oxocyclobutanecarboxylic acid (CAS 2228641-38-9)
- 1-(Difluoromethyl)-3-nitro-1H-1,2,4-triazole (CAS 2137653-18-8)
Recommended Standards
- 2,2,2-Trifluoroethanesulfonic acid (CAS 1827-97-0)
- 1,2,3,4-Tetrafluoro-5-methylbenzene (CAS 21622-19-5)
- 2,3,5,6-Tetrafluorotoluene (CAS 5230-78-4)
- 3-[Ethyl(hydroxy)phosphoryl]prop-2-enoic acid (CAS 1086274-70-5)
- 5-(Trifluoromethoxy)benzofuran-3(2H)-one (CAS 944899-99-4)
- 2-Amino-3-hydroxy-2-methylpropyl hydrogen (5-bromo-4-chloro-1H-indol-3-yl)phosphonate (CAS 107475-11-6)
- 9N3UK29E57 7446-08-4 Selenium dioxide Selenium oxide Selenium oxide (SeO2) Selenium(IV) dioxide (1:2) CCRIS 5820 EINECS 231-194-7 HSDB 677 NSC 56753 RCRA waste number U204 Selenious anhydride Selenium dioxide dimer Selenium oxide (1:2) Selenium oxide (Se2O4) Selenous acid anhydride UNII-9N3UK29E57 EC 231-194-7 RCRA waste no. U204 Selenium(IV) dioxide (CAS 7446-08-4)
- 2-Cyano-5-iodopyridine (CAS 41960-47-8)
- (2-Bromo-5-(difluoromethyl)-4-(trifluoromethyl)pyridin-3-yl)methanol (CAS 1805964-00-4)
- 4-Methyl-1,3-thiazole-2-carboximidamide hydrochloride (CAS 1461705-41-8)
- 3-(2,6-Difluorophenyl)azetidin-3-ol (CAS 1487953-63-8)
- Dabigatran Impurity 3 (CAS 1610758-22-9)
- Ugilec 141 (CAS 111483-93-3)
- Liraglutide-d8 Tetratrifluoroacetate (CAS 204656-20-2 (non-labelled, free base))
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