2,5-Bis(trifluoromethyl)phenylboronic Acid CAS 196083-18-8
| CAS No. | 196083-18-8 |
| Molecular Formula | C8H5BF6O2 |
| Molecular Weight | 257.93 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The occurrence of 2,5-Bis(trifluoromethyl)phenylboronic Acid is closely related to a carboxylic acid group, a hydroxyl group, an ether linkage, fluorine substitution in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.
CATO supplies 2,5-Bis(trifluoromethyl)phenylboronic Acid (CAS 196083-18-8), a certified reference material (molecular formula C8H5BF6O2, MW 257.93 g/mol) for analytical method development and quality control.
The molecular framework of 2,5-Bis(trifluoromethyl)phenylboronic Acid (C8H5BF6O2) is characterized by a carboxylic acid group, a hydroxyl group, an ether linkage, fluorine substitution. In reversed-phase chromatography, its retention is governed primarily by the polarity and ionization state of its functional groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
As a certified reference material (CRM), 2,5-Bis(trifluoromethyl)phenylboronic Acid meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C8H5BF6O2 |
| Molecular Weight | 257.93 g/mol |
| Purity | 97%+ |
| Storage | Store at room temperature, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 3.5 |
| UV Absorption | UV-absorbing |
| CAS Registry Year (est.) | 2013 |
| Halogen Content | F-containing |
Related Bis Standards
- 3,4-Bis(trifluoromethyl)phenylboronic Acid (CAS 1204745-88-9)
- 153254-09-2 2,4-Bis(trifluoromethyl)benzeneboronic Acid 2,4-Bis(trifluoromethyl)phenylboronic Acid B3022 (CAS 153254-09-2)
- (2,3-Bis(trifluoromethyl)phenyl)boronic acid (CAS 927673-87-8)
- 2,6-Bis(trifluoromethyl)phenylboronic Acid (CAS 681812-07-7)
- (4-Ethyl-2-(trifluoromethyl)-4H-pyrrolo[3,2-b]pyridin-6-yl)boronic acid (CAS 2918994-26-8)
- 3,4-Bis(trifluoromethyl)benzoic Acid (CAS 133804-66-7)
- 2,3-Bis(trifluoromethyl)benzoic acid (CAS 42175-55-3)
- 2,4 - Bis(trifluoromethyl)benzoic acid 2,4-Bis-trifluoromethyl-benzoic acid 32890-87-2 benzoic acid, 2,4-bis(trifluoromethyl)- (CAS 32890-87-2)
Recommended Standards
- 4-(Trichloromethyl)benzoyl chloride (CAS 14815-86-2)
- 2,2-Dichloro-1-(2,4-dichlorophenyl)ethanone (CAS 2274-66-0)
- 2-Bromo-5-(bromomethyl)-1,3,4-thiadiazole (CAS 1454906-50-3)
- 2,2-Dichloro-1-(2,6-dichlorophenyl)ethan-1-one (CAS 78710-01-7)
- 2-(Aminomethyl)-3-(p-tolyl)quinazolin-4(3H)-one (CAS 683737-38-4)
- S-(1, 2, 2-Trichlorovinyl)-Glutathione (CAS 111574-85-7)
- 2-(3-(Aminomethyl)piperidin-1-yl)-N-(2-methoxyethyl)acetamide (CAS 1292922-61-2)
- 2-(2,4-Dichlorophenoxy)-6-phenyl-4-(trifluoromethyl)pyridine-3-carbonitrile (CAS 338749-46-5)
- 3-Benzyloxycyclobutane-1,1-dicarboxylic acid ethyl ester (CAS 180205-43-0)
- 2-Chloro-N-(4-(piperidin-1-yl)phenyl)propanamide hydrochloride (CAS 1170148-51-2)
- 2,3,5-Trichloropyridine (CAS 16063-70-0)
- 3-Methoxy-4-((4-(methylsulfonyl)benzyl)oxy)aniline (CAS 15382-83-9)
- 1-[4-(aminomethyl)phenyl]ethan-1-amine dihydrochloride (CAS 1461714-89-5)
- Palmitoyl Tripeptide -5 ยท 2 TFA (CAS 623172-56-5)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com