6-Hydroxy-2-pyridinecarboxylic Acid CAS 19621-92-2
| CAS No. | 19621-92-2 |
| Molecular Formula | C6H5NO3 |
| Molecular Weight | 139.11 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including 6-Hydroxy-2-pyridinecarboxylic Acid.
6-Hydroxy-2-pyridinecarboxylic Acid (CAS 19621-92-2) is a high-purity analytical reference standard with the molecular formula C6H5NO3 and a molecular weight of 139.11 g/mol.
6-Hydroxy-2-pyridinecarboxylic Acid (C6H5NO3) contains an amino-acid-derived structure, an amide group, a hydroxyl group, an ether linkage. It is notably hygroscopic, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C6H5NO3 |
| Molecular Weight | 139.11 g/mol |
| Purity | >95% |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in methanol, ethanol, DMSO, water |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 5.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1962 |
| Nitrogen Atoms | 1 |
Related Hydroxy Standards
- 3-Hydroxy-4-pyridinecarboxylic acid, 97% (CAS 10128-71-9)
- 5-Hydroxy-Pyrazinamide (CAS 13924-96-4)
- 4-Hydroxy-3-pyridinecarboxylic Acid (CAS 609-70-1)
- 5-Hydroxy Nicotinic Acid (CAS 27828-71-3)
- 3-Hydroxy-2-pyridinecarboxylic Acid (CAS 874-24-8)
- 2-Hydroxy-4,4,4-trifluorobutyronitrile (CAS 912578-73-5)
- 5-Hydroxy-2-methoxy-4-methylpyridine (CAS 1086389-80-1)
- 3-Hydroxy-3-(tetrahydrofuran-2-yl)acrylonitrile (CAS 1221820-97-8)
Recommended Standards
- 2-Hydroxynicotinic Acid (CAS 609-71-2)
- 2-carboxypyridine 1-oxide (CAS 824-40-8)
- 2-Amino-pyrimidine-4-carboxylicacid 2-aminopyrimidine-4-carboxylic acid 2164-65-0 A18452 (CAS 2164-65-0)
- Topiroxostat Impurity 3 (CAS 13602-12-5)
- (E)-2-Methyl-3-(thiophen-2-yl)acrylic acid (CAS 102696-69-5)
- 4-Phenoxypicolinimidamide hydrochloride (CAS 1179360-92-9)
- 5-Chloroquinolin-8-yl p-tolylcarbamate (CAS 21617-07-2)
- Methyl 5-cyano-2-methyl-6-phenoxypyridine-3-carboxylate (CAS 303146-35-2)
- 4-((2,6-Difluorobenzyl)oxy)benzaldehyde (CAS 885269-73-8)
- 2-(2-(2-Oxopropoxy)phenoxy)acetic acid (CAS 27165-68-0)
- 6-Methyl-3-(2-thienyl)-1,2,4-triazin-5-ol (CAS 886360-71-0)
- 1-(4,5-Dichloro-1-methyl-1H-pyrazol-3-yl)-N-methylmethanamine (CAS 1006485-34-2)
- 2-(1-(2-Cyanophenyl)-2,5-dimethyl-1H-pyrrol-3-yl)-2-oxo-N-phenylacetamide (CAS 866144-06-1)
- Peptide Impurity 06 (CAS CATO-CPTD788806)
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