| CAS No. | 19677-11-3 |
| Molecular Formula | C17H13F3N2S |
| Molecular Weight | 334.36 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
2-Methyl-3-(2-(trifluoromethyl)-10H-phenothiazin-10-yl)propanenitrile (CAS 19677-11-3), molecular formula C17H13F3N2S and molecular weight 334.36 g/mol, is a CATO reference standard with documented purity and traceability.
2-Methyl-3-(2-(trifluoromethyl)-10H-phenothiazin-10-yl)propanenitrile (C17H13F3N2S) contains a nitrogen-containing heterocyclic scaffold, a nitrile group, sulfur-containing functionality, fluorine substitution. Halogen substitution raises its density and boiling point, its high carbon-to-hydrogen ratio confers good lipid solubility; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
| Molecular Formula | C17H13F3N2S |
| Molecular Weight | 334.36 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 11.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1962 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 2 |
| Sulfur Atoms | 1 |