8-Methyl-6-chloroisoquinoline CAS 196875-78-2
| CAS No. | 196875-78-2 |
| Molecular Formula | C10H8ClN |
| Molecular Weight | 177.63 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Compared with other compounds in its class, the molecular weight of 177.63 g/mol gives 8-Methyl-6-chloroisoquinoline distinctive chromatographic separation conditions and mass-spectrometry parameter settings.
8-Methyl-6-chloroisoquinoline (CAS 196875-78-2) is a high-purity analytical reference standard with the molecular formula C10H8ClN and a molecular weight of 177.63 g/mol.
The molecular framework of 8-Methyl-6-chloroisoquinoline (C10H8ClN) is characterized by a nitrogen-containing heterocyclic scaffold, a nitrile group, chlorine substitution. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
CATO manufactures 8-Methyl-6-chloroisoquinoline under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C10H8ClN |
| Molecular Weight | 177.63 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 7.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2013 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 1 |
Related Methyl Standards
- 5-Chloroisoquinoline 2-oxide (CAS 70810-25-2)
- 8-Chloroisoquinoline 2-oxide (CAS 70810-27-4)
- 1-Chloroisoquinoline-5-carbonitrile (CAS 1231761-23-1)
- 1-Chloroisoquinoline-8-carbonitrile (CAS 1231761-24-2)
- 5-Chloroisoquinoline-1-carbonitrile (CAS 1231761-25-3)
- 8-Chloroisoquinoline-1-carbonitrile (CAS 1231761-26-4)
- 4-Chloroisoquinoline-5-carbonitrile (CAS 1231761-27-5)
- 3-Chloroisoquinoline-1-carbonitrile (CAS 1237431-75-2)
Recommended Standards
- 6-Chloro-8-methylquinoline (CAS 19655-50-6)
- (Z)-3-chloro-3-p-tolylacrylonitrile (CAS 78583-85-4)
- 8-Chloro-6-methylquinoline (CAS 19655-46-0)
- 1-(2-Chlorophenyl)-1H-pyrrole (CAS 89096-75-3)
- 2,4-Dichloro-1-fluoro-3-nitro-5-(trifluoromethyl)benzene (CAS 1221272-80-5)
- 653584-64-6 A835086 N-[4-(hydroxymethyl)-3-pyridinyl]-2,2-dimethylpropanamide N-[4-(hydroxymethyl)pyridin-3-yl]-2,2-dimethyl-propanamide (CAS 653584-64-6)
- 6,7-Dihydroxy-3,4-dimethyl-2H-chromen-2-one (CAS 16574-11-1)
- tert-butyl (2,3-dimethyl-2H-indazol-6-yl)carbamate (CAS 2384038-16-6)
- Tert-butyl 4-(3-hydroxy-2-phenylpropyl)piperazine-1-carboxylate (CAS 189298-13-3)
- Methyl 15-hydroxypentadecanoate (CAS 76529-42-5)
- 4,4-Dimethyl-2-(propylsulfonyl)cyclohexan-1-amine (CAS 1342167-25-2)
- 5-Bromo-3-methylbenzo[d]isothiazole (CAS 73437-06-6)
- 3-(tert-Butoxycarbonyl)-3-azabicyclo[4.1.0]heptane-1-carboxylic acid (CAS 1239421-67-0)
- Semaglutide impurity 193 (CAS CATO-C4X-2226193)
Why CATO?
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