4-Nitro-1-naphthoic acid CAS 1975-43-5
| CAS No. | 1975-43-5 |
| Molecular Formula | C11H7NO4 |
| Molecular Weight | 217.18 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
CATO supplies 4-Nitro-1-naphthoic acid (CAS 1975-43-5), a certified reference material (molecular formula C11H7NO4, MW 217.18 g/mol) for analytical method development and quality control.
The molecular framework of 4-Nitro-1-naphthoic acid (C11H7NO4) is characterized by an amino-acid-derived structure, an amide group, a hydroxyl group, an ether linkage. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
As a certified reference material (CRM), 4-Nitro-1-naphthoic acid meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C11H7NO4 |
| Molecular Weight | 217.18 g/mol |
| Appearance | Pale yellow to yellow crystalline powder |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in methanol, ethanol, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 9.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1957 |
| Nitrogen Atoms | 1 |
Related Nitro Standards
- 1-Nitro-2-naphthoic acid (CAS 103987-83-3)
- 5-Nitro-2-(1h-pyrazol-1-yl)benzaldehyde (CAS 1152558-90-1)
- 3-Nitro-4-(1h-pyrazol-1-yl)benzaldehyde (CAS 1152559-00-6)
- 4-Nitro-[2,2'-bipyridine] 1-oxide (CAS 14163-00-9)
- 6-Nitro-1-naphthoic acid (CAS 1975-45-7)
- 3-Nitro-2-naphthoic acid (CAS 73428-03-2)
- 4'-Nitro-[2,2'-bipyridine] 1-oxide (CAS 84175-05-3)
- 5'-Nitro-[2,3'-bipyridin]-6'(1'H)-one (CAS 62749-36-4)
Recommended Standards
- ACPT-II (CAS 195209-04-2)
- 5-nitronaphthalene-1-carboxylic acid (CAS 1975-44-6)
- ACPT-I (CAS 194918-76-8)
- 2-(4-Nitrophenoxy)pyrimidine (CAS 181801-29-6)
- (E)-N'-cyano(methylsulfanyl)methanimidamide (CAS 860354-94-5)
- N,N-Dimethyl-2-piperidin-4-ylacetamidehydrochloride (CAS 1269053-84-0)
- 1-(3-Chlorophenyl)-3-methyl-4-[3-(trifluoromethyl)phenyl]-1H-pyrazol-5-amine (CAS 477708-95-5)
- n-Methyl-1-(2-methylfuran-3-yl)methanamine hydrochloride (CAS 1211842-31-7)
- (E)-5-(2-Fluorobenzylidene)-2-mercaptothiazol-4(5H)-one (CAS 1784763-12-7)
- 3-Amino-N-(2,4-difluorophenyl)-6-ethyl-5H,6H,7H,8H-thieno[2,3-b]quinoline-2-carboxamide (CAS 445269-11-4)
- Methyl 3-hydroxypentanoate (CAS 56009-31-5)
- 3-Nitro-5-pyrrolidin-1-ylpyridin-2-ol (CAS 1706457-56-8)
- 2,2,2-Trifluoro-1-(4-(trifluoromethyl)phenyl)ethan-1-amine hydrochloride (CAS 1220039-72-4)
- Semaglutide impurity 202 (CAS CATO-C4X-2226202)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com