6-(4-Methylpiperazin-1-yl)-11H-dibenzo[b,e]azepine CAS 1977-11-3
| CAS No. | 1977-11-3 |
| Molecular Formula | C19H21N3 |
| Molecular Weight | 291.39 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including 6-(4-Methylpiperazin-1-yl)-11H-dibenzo[b,e]azepine.
6-(4-Methylpiperazin-1-yl)-11H-dibenzo[b,e]azepine (CAS 1977-11-3), molecular formula C19H21N3 and molecular weight 291.39 g/mol, is a CATO reference standard with documented purity and traceability.
6-(4-Methylpiperazin-1-yl)-11H-dibenzo[b,e]azepine (C19H21N3) contains a nitrogen-containing heterocyclic scaffold, a nitrile group. Its high carbon-to-hydrogen ratio confers good lipid solubility; these physicochemical properties determine the optimal preparation and storage of its standard solutions. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C19H21N3 |
| Molecular Weight | 291.39 g/mol |
| Appearance | Pale yellow to yellow crystalline powder |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 11.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1957 |
| Nitrogen Atoms | 3 |
Related Methylpiperazin Standards
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- 5-((2-Methylpiperazin-1-yl)sulfonyl)isoquinoline (CAS 84477-87-2)
- 5-((3-Methylpiperazin-1-yl)sulfonyl)isoquinoline (CAS 84477-73-6)
- [[2-(4-Methylpiperazin-1-yl)-2-oxoethyl](phenyl)-amino]acetic acid (CAS 1142205-97-7)
- 4-((4-(4-Methylpiperazin-1-yl)phenyl)amino)-4-oxobutanoic acid (CAS 724455-62-3)
- (4-Methyl-3-(3-(4-methylpiperazin-1-yl)propoxy)phenyl)boronic acid (CAS 1704064-31-2)
- 6-(4-Methylpiperazin-1-yl)-N-(2-(pyrrolidin-1-yl)ethyl)pyridazin-3-amine (CAS 920528-85-4)
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Recommended Standards
- 1-((R,2E,4E,6E)-8-hydroxy-6-methyldodeca-2,4,6-trienoyl)pyrrolidin-2-one (CAS 19504-77-9)
- (-)-Mesembranol (CAS 23544-42-5)
- Tert-butyl 4-(6-amino-5-methylpyridin-3-yl)piperidine-1-carboxylate (CAS 1947415-48-6)
- (2-((2,5-Dihydro-1H-pyrrol-1-yl)methyl)phenyl)(2,3-dimethylphenyl)methanone (CAS 898763-20-7)
- 7-Oxa-2-azaspiro[4.5]decane hydrochloride (CAS 1989659-08-6)
- 1-(Cyclobutylmethyl)-4-methyl-1H-pyrazol-5-amine (CAS 1389315-12-1)
- 2-[(2,2-Dimethylpropyl)amino]acetic acid (CAS 853373-99-6)
- 4-(3,5-Bis(trifluoromethyl)phenyl)-2-hydrazinylthiazole (CAS 886504-50-3)
- 2-(2-Bromopropyl)-3-methylpyridine (CAS 1484682-58-7)
- [2-(2-methyl-1h-imidazol-1-yl)phenyl]methanamine (CAS 876717-29-2)
- Ethyl 3-fluoro-4-methoxybenzoate (CAS 170645-87-1)
- (1R)-(6-Methoxyquinolin-4-yl)((2S,4S,5R)-5-vinylquinuclidin-2-yl)methyl pentanoate (CAS 549-66-6)
- Doxylamine impurity 23 (CAS CATO-C4X-178923)
- Semaglutide impurity 43 (CAS CATO-C4X-222643)
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