N-(2-Fluorobenzoyl)morpholine CAS 1978-64-9
| CAS No. | 1978-64-9 |
| Molecular Formula | C11H12FNO2 |
| Molecular Weight | 209.22 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including N-(2-Fluorobenzoyl)morpholine.
N-(2-Fluorobenzoyl)morpholine (CAS 1978-64-9), molecular formula C11H12FNO2 and molecular weight 209.22 g/mol, is a CATO reference standard with documented purity and traceability.
N-(2-Fluorobenzoyl)morpholine (C11H12FNO2) contains a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, fluorine substitution. Halogen substitution raises its density and boiling point, its high carbon-to-hydrogen ratio confers good lipid solubility, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C11H12FNO2 |
| Molecular Weight | 209.22 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 6.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1957 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 1 |
Related N Standards
- N-(4-Fluorobenzoyl)morpholine (CAS 1978-65-0)
- (3s)-1-(4-Fluorobenzoyl)pyrrolidin-3-amine (CAS 1286207-57-5)
- (3r)-1-(4-Fluorobenzoyl)pyrrolidin-3-amine (CAS 1286208-64-7)
- 4-(4-Fluorobenzoyl)oxane (CAS 1342548-85-9)
- 1-(2-Fluorobenzoyl)piperazine (CAS 139516-64-6)
- 1-(3-Fluorobenzoyl)piperazine (CAS 179334-10-2)
- 1-(4-Fluorobenzoyl)cyclopropanecarboxylic acid (CAS 1191284-11-3)
- Methyl (3-fluorobenzoyl)glycinate (CAS 131648-59-4)
Recommended Standards
- methyl 5-fluoro-1,2,3,4-tetrahydroisoquinoline-8-carboxylate (CAS 1949793-11-6)
- 8-Ethyl-7-fluoro-5-hydroxy-3,4-dihydroquinolin-2(1H)-one (CAS 1883750-12-6)
- ((3R,4R)-3-fluoro-4-hydroxypyrrolidin-1-yl)(phenyl)methanone (CAS 2166108-02-5)
- N-[1-(2-fluorophenyl)-2-oxopropyl]-acetamide (CAS 186036-07-7)
- (4-(Fluoromethyl)tetrahydro-2H-pyran-4-yl)methanamine hydrochloride (CAS 1955558-25-4)
- Methyl 5-(Bromomethyl)nicotinate (CAS 877624-38-9)
- (E)-2-((3-cyanoallyl)thio)-4,6-dimethylnicotinonitrile (CAS 339276-61-8)
- 1-(Quinazolin-2-yl)guanidine (CAS 102331-12-4)
- tert-Butyl 6-(hydroxymethyl)-5-oxa-2-azaspiro[3.4]octane-2-carboxylate (CAS 1446012-48-1)
- 1-(4-Chloro-2-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl)ethanone (CAS 1350374-40-1)
- H-Arg-Gly-OH · HCl (CAS 105241-88-1)
- 4-(3,4-Dimethylphenyl)-2-hydrazono-5-methyl-2,3-dihydrothiazole (CAS 886494-51-5)
- 4-(2,5-Dimethyl-pyrrol-1-yl)-2-hydroxy-benzoic acid 4-(2,5-dimethyl-1H-pyrrol-1-yl)-2-hydroxybenzoic acid 5987-00-8 (CAS 5987-00-8)
- Semaglutide impurity 24 (CAS CATO-C4X-222624)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com