(2E)-4-[(3,4-Dimethylphenyl)amino]-4-oxobut-2-enoic acid CAS 198220-55-2
| CAS No. | 198220-55-2 |
| Molecular Formula | C12H13NO3 |
| Molecular Weight | 219.24 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
CATO manufactures (2E)-4-[(3,4-Dimethylphenyl)amino]-4-oxobut-2-enoic acid under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
(2E)-4-[(3,4-Dimethylphenyl)amino]-4-oxobut-2-enoic acid (CAS 198220-55-2) is a high-purity analytical reference standard with the molecular formula C12H13NO3 and a molecular weight of 219.24 g/mol.
Owing to an amino-acid-derived structure, an amide group, a hydroxyl group, an ether linkage, (2E)-4-[(3,4-Dimethylphenyl)amino]-4-oxobut-2-enoic acid is typically off-white to pale yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 219.24 g/mol — guide the selection of appropriate sample preparation and analytical techniques. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
Physical & Chemical Properties
| Molecular Formula | C12H13NO3 |
| Molecular Weight | 219.24 g/mol |
| Appearance | Off-white to pale yellow crystalline powder |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 7.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2013 |
| Nitrogen Atoms | 1 |
Related E Standards
- (E)-4-((2,6-Dimethylphenyl)amino)-4-oxobut-2-enoic acid (CAS 109017-95-0)
- 3-(2,5-dimethylphenyl)-4,5-dihydro-1,2-oxaZole-5-carboxylic acid (CAS 1247189-55-4)
- (2Z)-3-[(2,3-dimethylphenyl)carbamoyl]prop-2-enoic Acid (CAS 198220-51-8)
- (E)-4-((3,5-dimethylphenyl)amino)-4-oxobut-2-enoic acid (CAS 929697-66-5)
- (Z)-4-((2,6-dimethylphenyl)amino)-4-oxobut-2-enoic acid (CAS 31460-31-8)
- 4-((2,4-Dimethylphenyl)amino)-4-oxobut-2-enoic acid (CAS 198220-52-9)
- 4-((2,6-Dimethylphenyl)amino)-4-oxobut-2-enoic acid (CAS 198220-53-0)
- 4-(3,4-Dimethylphenyl)pyrrolidine-3-carboxylic acid (CAS 1342529-53-6)
Recommended Standards
- (1-Benzyl-1H-1,2,3-triazole-4,5-diyl)dimethanol (CAS 77177-20-9)
- (2-oxo-4-phenylpyrrolidin-1-yl)acetic Acid (CAS 67118-34-7)
- (1-[(4-Methoxyphenyl)methyl]-1h-1,2,3-triazol-4-yl)methanol (CAS 853807-55-3)
- (2R,3R)-1-Methyl-5-oxo-2-phenylpyrrolidine-3-carboxylic acid (CAS 461045-28-3)
- (1-(4-Chlorophenyl)-1H-1,2,3-triazol-4-yl)methanamine (CAS 886361-79-1)
- (2S,4R)-4-fluoropyrrolidine-2-carbonitrile hydrochloride (CAS 2306249-26-1)
- 155551-61-4 3a-Epiburchellin (CAS 155551-61-4)
- (2-Methylbenzofuro[3,2-d]pyrimidin-4-yl)-DL-proline (CAS 1008673-77-5)
- 5,6,7,8-Tetrahydronaphthalen-1-amine hydrochloride (CAS 6271-86-9)
- 2,2-Difluoro-1-(2-fluoro-4-methoxyphenyl)ethan-1-one (CAS 1022154-92-2)
- (1R)-1-benzo[b]thiophen-3-ylethylamine (CAS 1007881-38-0)
- (4-Methoxyphenyl)(thiophen-2-yl)methanone (CAS 4160-63-8)
- 2-Chloropyridine-3,4-dicarboxylic acid (CAS 215306-02-8)
- Insulin Glargine (CAS 160337-95-1)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com