Pyridine-4(1H)-thione CAS 19829-29-9

Description

Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including Pyridine-4(1H)-thione.

Pyridine-4(1H)-thione (CAS 19829-29-9), molecular formula C5H5NS and molecular weight 111.16 g/mol, is a CATO reference standard with documented purity and traceability.

Owing to a nitrile group, sulfur-containing functionality, Pyridine-4(1H)-thione is typically off-white to pale yellow liquid. Its solid-state physicochemical attributes — including a molecular weight of 111.16 g/mol — guide the selection of appropriate sample preparation and analytical techniques. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.

This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.

As a certified reference material (CRM), Pyridine-4(1H)-thione meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.

Physical & Chemical Properties

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