[1,1-Biphenyl]-4-carboxylic acid, 4-fluoro-2-hydroxy-, methyl ester CAS 198994-01-3
| CAS No. | 198994-01-3 |
| Molecular Formula | C14H11FO3 |
| Molecular Weight | 246.23 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The occurrence of [1,1-Biphenyl]-4-carboxylic acid, 4-fluoro-2-hydroxy-, methyl ester is closely related to a carboxylic acid group, a hydroxyl group, an ether linkage, fluorine substitution, a polycyclic aromatic system in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.
CATO supplies [1,1-Biphenyl]-4-carboxylic acid, 4-fluoro-2-hydroxy-, methyl ester (CAS 198994-01-3), a certified reference material (molecular formula C14H11FO3, MW 246.23 g/mol) for analytical method development and quality control.
Owing to a carboxylic acid group, a hydroxyl group, an ether linkage, fluorine substitution, a polycyclic aromatic system, [1,1-Biphenyl]-4-carboxylic acid, 4-fluoro-2-hydroxy-, methyl ester is typically pale yellow to yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 246.23 g/mol — guide the selection of appropriate sample preparation and analytical techniques. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
CATO manufactures [1,1-Biphenyl]-4-carboxylic acid, 4-fluoro-2-hydroxy-, methyl ester under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C14H11FO3 |
| Molecular Weight | 246.23 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 9.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2013 |
| Halogen Content | F-containing |
Related Biphenyl Standards
- [1,1'-Biphenyl]-2,2'-diyldimethanethiol (CAS 17749-54-1)
- 42973-13-7 (Biphenyl-4-yloxy)acetyl chloride MFCD11107993 (CAS 42973-13-7)
- (S)-1-([1,1'-Biphenyl]-4-yl)-3-chloropropan-2-ol, 97% (CAS 1573000-28-8)
- [1,1'-Biphenyl]-4-ylchlorodimethylsilane (CAS 41081-31-6)
- 4-([1,1'-Biphenyl]-4-yl)pyrimidin-2-amine (CAS 299463-56-2)
- [1,1'-Biphenyl]-4-ylmethanesulfonamide (CAS 89566-26-7)
- 2'-Methyl-[1,1'-biphenyl]-2-sulfonamide (CAS 217498-86-7)
- n-([1,1'-biphenyl]-4-yl)methanesulfonamide (CAS 724743-56-0)
Recommended Standards
- (5AR,9aS)-1-(trifluoromethyl)-4,5,5a,6,7,8,9,9a-octahydro-[1,2,4]triazolo[4,3-a][1,6]naphthyridine (CAS 2227198-58-3)
- 1-(3-(Trifluoromethoxy)phenyl)piperazine (CAS 54711-69-2)
- (1S,3s)-3-(benzyloxy)-1-(trifluoromethyl)cyclobutan-1-ol (CAS 2477877-26-0)
- 1-[4-(Trifluoromethoxy)phenyl]pentan-1-one (CAS 79619-25-3)
- N,N'-Dicyclohexylmorpholine-4-carboximidamide ((2R,3S,4R,5R)-5-(6-amino-9H-purin-9-yl)-3,4-dihydroxytetrahydrofuran-2-yl)methyl morpholinophosphonate (CAS 24558-92-7)
- Tucatinib (CAS 937263-43-9)
- (3-((Thietan-3-ylamino)methyl)cyclohexyl)methanol (CAS 1882472-62-9)
- (R)-tert-Butyl (1-(pyrrolidin-3-yl)cyclopropyl)carbamate oxalate (CAS 851388-56-2)
- 3-nitroimidazo[1,2-b]pyridazine (CAS 18087-75-7)
- 4-(2-Pyrrolidinylmethyl)-2-piperazinonedihydrochloride (CAS 1220027-47-3)
- 4-Aminomorpholine (CAS 4319-49-7)
- Lacosamide EP Impurity D (R-isomer) (CAS 196601-69-1)
- 5-Phenylpyrazolo[1,5-a]pyrimidine-7-carboxylic acid (CAS 1011355-77-3)
- Peptide Impurity 09 X TFA Salt (CAS CATO-CPTD788809)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com