N-(4-Fluorophenyl)-2-methylbenzamide CAS 199121-61-4
| CAS No. | 199121-61-4 |
| Molecular Formula | C14H12FNO |
| Molecular Weight | 229.25 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
N-(4-Fluorophenyl)-2-methylbenzamide (CAS 199121-61-4), molecular formula C14H12FNO and molecular weight 229.25 g/mol, is a CATO reference standard with documented purity and traceability.
The molecular framework of N-(4-Fluorophenyl)-2-methylbenzamide (C14H12FNO) is characterized by a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, fluorine substitution. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
As a certified reference material (CRM), N-(4-Fluorophenyl)-2-methylbenzamide meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C14H12FNO |
| Molecular Weight | 229.25 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 9.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2013 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 1 |
Related N Standards
- 4-(2-Fluorophenyl)-2-methyl-1-(prop-2-yn-1-yl)-1H-imidazol-5-amine (CAS 1269528-36-0)
- 4-(4-Fluorophenyl)-2-methyl-1-(prop-2-yn-1-yl)-1H-imidazol-5-amine (CAS 1269534-48-6)
- 2-(4-Fluorophenyl)-6,7-dihydro-5H-cyclopenta[d]pyrimidin-4-amine (CAS 1283543-69-0)
- 2-(3-Fluorophenyl)-6,7-dihydro-5H-cyclopenta[d]pyrimidin-4-amine (CAS 1311186-74-9)
- 3-(2-Fluorophenyl)-3,4-dihydro-2H-benzo[b][1,4]oxazine (CAS 1360820-21-8)
- 2-(4-Fluorophenyl)-5,6,7,8-tetrahydropyrido[4,3-d]pyrimidine (CAS 1395493-28-3)
- 3-(4-Fluorophenyl)-3,4-dihydro-2H-benzo[b][1,4]oxazine (CAS 1449790-88-8)
- 4-((3-Fluorophenyl)(methyl)amino)benzaldehyde (CAS 1455672-92-0)
Recommended Standards
- N-(4-Fluorophenyl)-1-(4-methoxyphenyl)methanimine (CAS 3381-48-4)
- N-(4-Fluorophenyl)-3-methylbenzamide (CAS 198879-86-6)
- N-(4-Fluorobenzylidene)-4-methoxyaniline (CAS 39769-08-9)
- N-(5-Fluoro-2-methylphenyl)benzamide (CAS 451-00-3)
- (R)-4-Cyano-N-(1-(1-ethyl-6-(trifluoromethyl)-1H-benzo[d]imidazol-2-yl)ethyl)benzenesulfonamide (CAS 1025506-51-7)
- 3-Methoxy-4-(trifluorometyl)phenylacetonitrile (CAS 1214372-99-2)
- 2-Chloro-5-[(pyrrolidin-1-yl)carbonyl]pyridine (CAS 64614-47-7)
- 1,1-Dimethylethyl N-[1-methyl-2-(4-morpholinyl)-2-oxoethyl]carbamate (CAS 796046-03-2)
- β-D-Allose (CAS 7283-09-2)
- 9-(3-Aminobenzyl)-N,N-dimethyl-9H-purin-6-amine (CAS 115204-50-7)
- 5-Methoxybenzofuran-2-carbaldehyde (CAS 23145-19-9)
- 2-Iodo-4-methyl-1-nitrobenzene 3-Iodo-4-nitrotoluene 52488-29-6 A19672 (CAS 52488-29-6)
- 3-(oxetan-3-yl)propan-1-ol (CAS 251922-47-1)
- Semaglutide impurity 62 (CAS CATO-C4X-222662)
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