6-Chloro-3h-imidazo[4,5-b]pyridine-2-thiol CAS 19918-37-7
| CAS No. | 19918-37-7 |
| Molecular Formula | C6H4ClN3S |
| Molecular Weight | 185.63 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including 6-Chloro-3h-imidazo[4,5-b]pyridine-2-thiol.
6-Chloro-3h-imidazo[4,5-b]pyridine-2-thiol (CAS 19918-37-7) is a high-purity analytical reference standard with the molecular formula C6H4ClN3S and a molecular weight of 185.63 g/mol.
Owing to a nitrile group, sulfur-containing functionality, chlorine substitution, an aromatic ring system, 6-Chloro-3h-imidazo[4,5-b]pyridine-2-thiol is typically off-white to pale yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 185.63 g/mol — guide the selection of appropriate sample preparation and analytical techniques. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
As a certified reference material (CRM), 6-Chloro-3h-imidazo[4,5-b]pyridine-2-thiol meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C6H4ClN3S |
| Molecular Weight | 185.63 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 6.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1962 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 3 |
| Sulfur Atoms | 1 |
Related Chloro Standards
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Recommended Standards
- 6-Chloro-1H-imidazo[4,5-c]pyridine-2(3H)-thione (CAS 7239-79-4)
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- 6-Chloro-1,2-benzisothiazol-3(2H)-one (CAS 70-10-0)
- 6-Chlorobenzoxazole-2(3H)-thione (CAS 22876-20-6)
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