(S)-6-Fluoro-2-methyl-1,2,3,4-tetrahydroquinoline CAS 199186-68-0
| CAS No. | 199186-68-0 |
| Molecular Formula | C10H12FN |
| Molecular Weight | 165.21 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
CATO supplies (S)-6-Fluoro-2-methyl-1,2,3,4-tetrahydroquinoline (CAS 199186-68-0), a certified reference material (molecular formula C10H12FN, MW 165.21 g/mol) for analytical method development and quality control.
The molecular framework of (S)-6-Fluoro-2-methyl-1,2,3,4-tetrahydroquinoline (C10H12FN) is characterized by a nitrogen-containing heterocyclic scaffold, a nitrile group, fluorine substitution. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C10H12FN |
| Molecular Weight | 165.21 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 5.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2013 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 1 |
Related S Standards
- 8-Fluoro-3-methyl-1,2,3,4-tetrahydroquinoline (CAS 1017138-99-6)
- (R)-7-Fluoro-1,2,3,4-tetrahydronaphthalen-1-amine (CAS 1055949-62-6)
- (R)-6-Fluoro-1,2,3,4-tetrahydronaphthalen-1-amine (CAS 1057246-78-2)
- 8-fluoro-1-methyl-1,2,3,4-tetrahydroisoquinoline (CAS 1176414-86-0)
- 9-Fluoro-2,3,4,5-tetrahydro-1H-benzo[c]azepine (CAS 1185110-93-3)
- (4-Fluoro-2,3-dihydro-1H-inden-1-yl)methanamine (CAS 1188164-05-7)
- 8-Fluoro-1,2,3,4-tetrahydronaphthalen-1-amine (CAS 1199782-71-2)
- (S)-5-fluoro-6-methyl-2,3-dihydro-1H-inden-1-amine (CAS 1212922-81-0)
Recommended Standards
- (S)-6-Fluoro-1,2,3,4-tetrahydro-naphthalen-2-ylamine (CAS 782427-32-1)
- (S)-7-Fluoro-1,2,3,4-tetrahydronaphthalen-1-amine (CAS 462105-66-4)
- (S)-5-fluoro-1,2,3,4-tetrahydronaphthalen-2-amine (CAS 740779-66-2)
- (S)-7-fluoro-1,2,3,4-tetrahydronaphthalen-2-amine (CAS 732965-99-0)
- (S)-3-((((9H-Fluoren-9-yl)methoxy)carbonyl)amino)-4-(tert-butoxy)butanoic acid (CAS 1820583-73-0)
- 2-Methoxy-3-nitropyridine hydrate (CAS 1881328-81-9)
- 4-(Piperidin-4-yl)pyridin-2-amine (CAS 1159822-14-6)
- (3E,5E)-3,5-Bis[(4-ethylphenyl)methylidene]-1-methylpiperidin-4-ol (CAS 380626-15-3)
- 1-(4-Ethoxy-3,5-dimethylphenyl)-2,2,2-trifluoroethan-1-one (CAS 1443349-44-7)
- 1,2,3,4-tetrahydrophenanthrene-9-carboxylic acid 102630-80-8 KST-1A9613 (CAS 102630-80-8)
- Zuclopenthixol acetate (CAS 85721-05-7)
- 2,6-Dichloro-5-(difluoromethyl)pyridin-3-amine (CAS 1805969-53-2)
- 2-(1-Imidazolyl)aniline (CAS 26286-54-4)
- Semaglutide impurity 99 (CAS CATO-C4X-222699)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com