3,3,3-Trifluoro-2-(5-methoxy-1h-indol-3-yl)propanoic acid CAS 1993086-13-7
| CAS No. | 1993086-13-7 |
| Molecular Formula | C12H10F3NO3 |
| Molecular Weight | 273.21 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
3,3,3-Trifluoro-2-(5-methoxy-1h-indol-3-yl)propanoic acid (CAS 1993086-13-7), molecular formula C12H10F3NO3 and molecular weight 273.21 g/mol, is a CATO reference standard with documented purity and traceability.
3,3,3-Trifluoro-2-(5-methoxy-1h-indol-3-yl)propanoic acid (C12H10F3NO3) contains a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, fluorine substitution. It is notably hygroscopic, halogen substitution raises its density and boiling point, its high carbon-to-hydrogen ratio confers good lipid solubility, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
As a certified reference material (CRM), 3,3,3-Trifluoro-2-(5-methoxy-1h-indol-3-yl)propanoic acid meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C12H10F3NO3 |
| Molecular Weight | 273.21 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 7.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1996 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 1 |
Related Trifluoro Standards
- Methyl 3,3,3-trifluoro-2-hydroxy-2-(1H-indol-3-yl)propanoate (CAS 114125-58-5)
- 2,2,2-Trifluoro-N-(6-methoxy-3-oxo-2,3-dihydro-1H-inden-1-yl)acetamide (CAS 138621-65-5)
- 2,2,2-Trifluoro-N-(4-methoxy-3-oxo-2,3-dihydro-1H-inden-1-yl)acetamide (CAS 861209-50-9)
- 3,3,3-Trifluoro-2-(4-(trifluoromethyl)phenoxy)propan-1-amine (CAS 886764-46-1)
- Methyl 2,3,5-trifluoro-4-(piperidin-1-yl)benzoate (CAS 1858249-59-8)
- Ethyl 3,3,3-trifluoro-2-((1-phenylethylidene)amino)propanoate (CAS 193140-70-4)
- 2,2,2-Trifluoro-1-(3-(2-methoxyphenyl)pyrrolidin-1-yl)ethanone (CAS 648901-36-4)
- 3,3,3-Trifluoro-2-((1,2,3,4-tetrahydroquinolin-2-yl)methyl)propanoic acid (CAS 690632-20-3)
Recommended Standards
- 2-Trifluoromethyl-α-acetamidocinnamic Acid (CAS 3094-32-4)
- 4-[3-(Trifluoromethyl)-[1,2,4]triazolo[4,3-b]pyridazin-6-yl]morpholine (CAS 312617-37-1)
- 5-Isopropyl-3-(4-(trifluoromethyl)pyridin-2-yl)-1,3,4-oxadiazol-2(3H)-one (CAS 883010-99-9)
- 2-(3,6-Dimethyl-4-(trifluoromethyl)-1H-pyrazolo[3,4-b]pyridin-1-yl)acetic acid (CAS 866769-95-1)
- N-(7H-Purin-6-yl)hydroxylamine (CAS 5667-20-9)
- 5-Hydroxy-2,6-dimethylpyridazin-3(2H)-one (CAS 869357-37-9)
- 7,7-Dimethyl-1,5,6,7-tetrahydroindeno[5,6-d]imidazol-5-amine (CAS 1248565-23-2)
- Z-Trp(Boc)-OH · DCHA (CAS 218938-57-9)
- 2-Hydroxy-5-iodobenzenesulfonamide (CAS 1243475-97-9)
- tert-Butyl 4-(benzylamino)-3-fluoropiperidine-1-carboxylate (CAS 934536-09-1)
- ethyl 4-(4-aminophenyl)-4-oxobutanoate (CAS 6335-44-0)
- germanium dichloride-dioxane complex (CAS 10060-11-4)
- 4-((3-(2-Nitrophenyl)allylidene)amino)-3-(m-tolyl)-1H-1,2,4-triazole-5(4H)-thione (CAS 478256-33-6)
- D-Leu26-Tirzepatide (CAS CATO-CPTD788908)
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