Ethyl 2-chloro-6-(4-bromophenyl)nicotinate CAS 1993196-89-6
| CAS No. | 1993196-89-6 |
| Molecular Formula | C14H11BrClNO2 |
| Molecular Weight | 340.60 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including Ethyl 2-chloro-6-(4-bromophenyl)nicotinate.
CATO supplies Ethyl 2-chloro-6-(4-bromophenyl)nicotinate (CAS 1993196-89-6), a certified reference material (molecular formula C14H11BrClNO2, MW 340.60 g/mol) for analytical method development and quality control.
The molecular framework of Ethyl 2-chloro-6-(4-bromophenyl)nicotinate (C14H11BrClNO2) is characterized by a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, chlorine/bromine substitution. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
As a certified reference material (CRM), Ethyl 2-chloro-6-(4-bromophenyl)nicotinate meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C14H11BrClNO2 |
| Molecular Weight | 340.60 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 9.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1996 |
| Halogen Content | Cl/Br-containing |
| Nitrogen Atoms | 1 |
Related Ethyl Standards
- Ethyl 2-chloro-6-(3-bromophenyl)nicotinate (CAS 1987007-85-1)
- Ethyl 2-(3-chloro-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenoxy)acetate (CAS 1218789-47-9)
- 1-(3-Chloro-5-(trifluoromethyl)pyridin-2-yl)-5-(trifluoromethyl)-1H-pyrazole-4-carbonitrile (CAS 318951-58-5)
- 2-Chloro-1-(4-iodobutoxy)-4-methoxybenzene (CAS 73523-71-4)
- 2-Chloro-5-(5,6-dichloro-1H-indol-2-yl)benzoic acid (CAS 835595-01-2)
- 5-Chloro-1-(2,6-dichlorobenzyl)indoline-2,3-dione (CAS 252579-05-8)
- 5-Chloro-1-[(3,4-dichlorophenyl)methyl]-2,3-dihydro-1H-indole-2,3-dione (CAS 79183-32-7)
- 2-(3-Chloro-2-isopropyl-5-(methoxymethoxy)phenyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane (CAS 2621936-47-6)
Recommended Standards
- N-(2-Bromophenyl)-5-chloro-2-methoxybenzamide (CAS 349538-99-4)
- 5-Bromo-2-chloro-N-(2-(pyrimidin-5-yl)ethyl)benzamide (CAS 2034482-11-4)
- N-(4-Bromo-2-chlorophenyl)-2-methoxybenzamide (CAS 842117-64-0)
- 4-Bromo-N-(3-chloro-4-methoxyphenyl)benzamide (CAS 449166-30-7)
- N-(4-(benzo[d]oxazol-2-yl)phenyl)-4-chlorobenzamide (CAS 339582-28-4)
- 4-Methyl-2-(3-nitrophenyl)thiazole-5-carboxylic acid (CAS 15911-29-2)
- 5-(1-Isopropylpyrrolidin-2-yl)-N,N,3-trimethylpyridin-2-amine (CAS 1352497-91-6)
- Methyl 3-cyclohexylpropiolate (CAS 42134-60-1)
- 3-Methoxy-N-methylacridin-9-amine (CAS 61299-60-3)
- Ambroxol Impurity 49 (CAS 86379-71-7)
- 1-((2,5-Difluorophenyl)sulfonyl)piperazine (CAS 847837-33-6)
- 3-(3-Chloro-5-fluorophenyl)prop-2-yn-1-ol (CAS 215054-57-2)
- 2-Chloro-5,6-dimethylpyridine-3-carbaldehyde (CAS 65176-92-3)
- D-Ala21-Tirzepatide (CAS CATO-CPTD788913)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com