6-Iodo-2(3H)-benzoxazolone CAS 19932-87-7
| CAS No. | 19932-87-7 |
| Molecular Formula | C7H4INO2 |
| Molecular Weight | 261.02 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including 6-Iodo-2(3H)-benzoxazolone.
CATO supplies 6-Iodo-2(3H)-benzoxazolone (CAS 19932-87-7), a certified reference material (molecular formula C7H4INO2, MW 261.02 g/mol) for analytical method development and quality control.
The molecular framework of 6-Iodo-2(3H)-benzoxazolone (C7H4INO2) is characterized by an amide group, a carboxylic acid group, a hydroxyl group, an ether linkage, iodine substitution, an aromatic ring system. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C7H4INO2 |
| Molecular Weight | 261.02 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 6.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1962 |
| Halogen Content | I-containing |
| Nitrogen Atoms | 1 |
Related Iodo Standards
- 7-Iodo-1H-pyrrolo[3,2-d]pyrimidin-4(5H)-one (CAS 1239602-17-5)
- 7-Iodo-[1,2,4]triazolo[4,3-a]pyridin-3(2H)-one (CAS 1306554-49-3)
- 5-Iodo-1H-pyrazolo[3,4-b]pyridin-3(2H)-one (CAS 1379322-80-1)
- 5-Iodo-1H-pyrazolo[3,4-b]pyrazin-3-amine (CAS 1392149-77-7)
- 3-Iodo-3H-Pyrazolo[3,4-d]Pyrimidin-4-Amine (CAS 151266-23-8)
- 3-Iodo-1H-pyrazolo[4,3-d]pyrimidin-7-amine (CAS 162791-82-4)
- 3-Iodo-1H-pyrazolo[4,3-d]pyrimidin-5-amine (CAS 1934520-91-8)
- 3-Iodo-1H-pyrazolo[3,4-d]pyrimidin-6-amine (CAS 1935147-85-5)
Recommended Standards
- 6-Iodo-[1,2,4]triazolo[4,3-a]pyridin-3(2h)-one (CAS 690258-19-6)
- 7-Bromo-5,8-difluoroquinazolin-4(3H)-one (CAS 2250340-29-3)
- 5-Iodobenzo[d]isoxazol-3(2H)-one (CAS 855996-68-8)
- 7-Iodoimidazo[2,1-f][1,2,4]triazin-4-amine (CAS 2379321-14-7)
- 4-Oxo-2-phenylquinazolin-3(4H)-yl 4-chlorobenzenesulfonate (CAS 130536-25-3)
- Kalopanaxsaponin H (CAS 128730-82-5)
- (3-Aminopiperidin-1-yl)(2-methoxypyridin-3-yl)methanone (CAS 1409396-83-3)
- 6,6'-(((2,2-Dimethylpropane-1,3-diyl)bis(oxy))bis(carbonyl))bis(cyclohex-3-ene-1-carboxylic acid) (CAS 41026-17-9)
- trans-1-Butoxy-4-(4-propylcyclohexyl)benzene (CAS 79709-84-5)
- Moxifloxacin impurity 172 (CAS CATO-C4X-1074172)
- Diethyl 9H-carbazole-3,6-dicarboxylate (CAS 3215-42-7)
- Gefitinib Impurity 84 (CAS CATO-C4X-111784)
- 2-Chloro-4,5-dimethylaniline (CAS 1585-13-3)
- [3-31]-Semaglutide D (Sodium salt) (CAS CATO-C4X-2226119)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com