1-(3-Bromo-5-fluorobenzyl)-3,3-difluoropyrrolidine CAS 1994538-79-2
| CAS No. | 1994538-79-2 |
| Molecular Formula | C11H11BrF3N |
| Molecular Weight | 294.11 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
CATO supplies 1-(3-Bromo-5-fluorobenzyl)-3,3-difluoropyrrolidine (CAS 1994538-79-2), a certified reference material (molecular formula C11H11BrF3N, MW 294.11 g/mol) for analytical method development and quality control.
The molecular framework of 1-(3-Bromo-5-fluorobenzyl)-3,3-difluoropyrrolidine (C11H11BrF3N) is characterized by a nitrogen-containing heterocyclic scaffold, a nitrile group, fluorine/bromine substitution. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
CATO manufactures 1-(3-Bromo-5-fluorobenzyl)-3,3-difluoropyrrolidine under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C11H11BrF3N |
| Molecular Weight | 294.11 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 5.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1996 |
| Halogen Content | F/Br-containing |
| Nitrogen Atoms | 1 |
Related Bromo Standards
- 1-(4-Bromo-3-trifluoromethylphenyl)pyrrolidine (CAS 1020252-86-1)
- (S)-2-(3-bromo-5-(trifluoromethyl)phenyl)pyrrolidine (CAS 1213135-02-4)
- (R)-2-(2-bromo-5-(trifluoromethyl)phenyl)pyrrolidine (CAS 1213376-40-9)
- (R)-2-(3-bromo-5-(trifluoromethyl)phenyl)pyrrolidine (CAS 1213598-20-9)
- (S)-(3-bromo-5-(trifluoromethyl)phenyl)(cyclopropyl)methanamine (CAS 1213843-98-1)
- (S)-1-(3-bromo-5-(trifluoromethyl)phenyl)but-3-en-1-amine (CAS 1269820-65-6)
- (R)-1-(3-bromo-5-(trifluoromethyl)phenyl)but-3-en-1-amine (CAS 1270041-22-9)
- 1-(3-Bromo-5-(trifluoromethyl)phenyl)-4-ethylpiperazine (CAS 1396780-06-5)
Recommended Standards
- 1-(5-Iodo-2-(methylthio)pyrimidin-4-yl)ethanone (CAS 1823367-54-9)
- 1-(4-Bromo-2-(trifluoromethyl)phenyl)pyrrolidine (CAS 895543-03-0)
- 1-(3-Bromo-4-(trifluoromethyl)phenyl)pyrrolidine 1779127-80-8 (CAS 1779127-80-8)
- 1-(4-Bromo-3-fluorobenzyl)-3,3-difluoropyrrolidine (CAS 2152775-63-6)
- ent-Florfenicol Amine-d3 (CAS 1217625-88-1)
- 4-Methyl-2-phenylthiazole-5-sulfonyl chloride (CAS 690632-88-3)
- 5-Bromo-1H-pyrrole-2-carbonitrile (CAS 36953-44-3)
- 2-amino-5-chloropyridine-3-carboxylic acid (CAS 52833-93-9)
- 3-(5-Chlorothiophen-2-yl)-2-methylprop-2-enal (CAS 1563958-97-3)
- 2'-(4-(2,4-Dichlorophenyl)thiazol-2-yl)-5,5'-dimethyl-2-phenyl-1',2'-dihydro-2H,3'H-[3,4'-bipyrazol]-3'-one (CAS 245039-21-8)
- (E)-N-methoxy-N'-(7-(1-(m-tolyloxy)ethyl)-[1,2,4]triazolo[1,5-a]pyrimidin-2-yl)formimidamide (CAS 477865-51-3)
- 4-Chloro-3-iodo-1-tosyl-1H-pyrrolo[2,3-b]pyridine (CAS 869335-20-6)
- 2-(Ethylamino)acetamide (CAS 98026-01-8)
- Semaglutide Impurity 192 (CAS CATO-C4X-2226192)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com