5-Bromo-8-(difluoromethoxy)quinoline CAS 199872-10-1
| CAS No. | 199872-10-1 |
| Molecular Formula | C10H6BrF2NO |
| Molecular Weight | 274.06 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
5-Bromo-8-(difluoromethoxy)quinoline (CAS 199872-10-1), molecular formula C10H6BrF2NO and molecular weight 274.06 g/mol, is a CATO reference standard with documented purity and traceability.
The molecular framework of 5-Bromo-8-(difluoromethoxy)quinoline (C10H6BrF2NO) is characterized by a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, fluorine/bromine substitution. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
CATO manufactures 5-Bromo-8-(difluoromethoxy)quinoline under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C10H6BrF2NO |
| Molecular Weight | 274.06 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 7.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2014 |
| Halogen Content | F/Br-containing |
| Nitrogen Atoms | 1 |
Related Bromo Standards
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Recommended Standards
- 5-(Dichloromethyl)-3-(4-nitrophenyl)-1,2,4-oxadiazole (CAS 905107-65-5)
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- 5-(Dichloromethyl)-3-(3-nitrophenyl)-1,2,4-oxadiazole (CAS 905107-54-2)
- 5-Iodo-1-methyl-1H-pyrazolo[3,4-b]pyridin-3-amine (CAS 766515-35-9)
- 2-Formylquinoline-8-carboxylic acid (CAS 904885-85-4)
- Methyl 2-methyl-6-oxo-4-(4-(trifluoromethyl)phenyl)-1,4,5,6-tetrahydropyridine-3-carboxylate (CAS 330216-62-1)
- 2-(2-Chloroethyl)-6-methylpyridine hydrochloride (CAS 17944-62-6)
- Ethyl 4-(4-(2,4-dichlorophenoxy)butanamido)benzoate (CAS 329938-35-4)
- 3-Amino-4-((2,6-dichlorophenyl)thio)benzonitrile (CAS 338982-10-8)
- 2-Methyl-4'-nitro-1,1'-biphenyl (CAS 33350-73-1)
- 2-(Chloromethyl)-3-methoxypyrazine (CAS 1211525-85-7)
- n-(3,4-Dichlorophenyl)-1h-indole-6-carboxamide (CAS 1147677-22-2)
- 4-(3-Chlorophenyl)-N-methylpiperazine-1-carbothioamide (CAS 457093-73-1)
- Antifreeze Polypeptide 6 (winter flounder) trifluoroacetate salt (CAS 122604-16-4)
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