8-Methoxy-2-(trifluoromethyl)quinoline-5-carboxylic acid CAS 199872-29-2
| CAS No. | 199872-29-2 |
| Molecular Formula | C12H8F3NO3 |
| Molecular Weight | 271.19 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
CATO supplies 8-Methoxy-2-(trifluoromethyl)quinoline-5-carboxylic acid (CAS 199872-29-2), a certified reference material (molecular formula C12H8F3NO3, MW 271.19 g/mol) for analytical method development and quality control.
Based on its molecular formula C12H8F3NO3, 8-Methoxy-2-(trifluoromethyl)quinoline-5-carboxylic acid contains a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, fluorine substitution; these features give the compound characteristic absorption bands in UV spectroscopy. The molecular weight of 271.19 g/mol is directly relevant to the identification of the molecular ion in mass spectrometry. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
As a certified reference material (CRM), 8-Methoxy-2-(trifluoromethyl)quinoline-5-carboxylic acid meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C12H8F3NO3 |
| Molecular Weight | 271.19 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 8.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2014 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 1 |
Related Methoxy Standards
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- 8-Methoxy-3-(trifluoromethyl)quinoline-6-carboxylic acid (CAS 2639205-59-5)
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Recommended Standards
- 5-Methyl-3-[4-(trifluoromethyl)phenyl]isoxazole-4-carboxylic Acid (CAS 943130-82-3)
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- 5-Methyl-2-[3-(trifluoromethyl)phenyl]oxazole-4-carboxylic Acid (CAS 848188-39-6)
- Ethyl 5,6,7-trifluoro-4-oxo-1,4-dihydroquinoline-3-carboxylate (CAS 836619-82-0)
- (1S,6R)-3-Boc-3,8-diazabicyclo[4.2.0]octane (CAS 370881-96-2)
- 2-(2-Chlorophenyl)-5,5-dimethylmorpholine (CAS 1017418-35-7)
- N-(4-Ethynylphenyl)cyclopropanecarboxamide (CAS 1842341-45-0)
- (1Z)-N-Hydroxy-3-methylbutanimidamide (CAS 691411-71-9)
- 4-bromo-3-ethyl-1H-pyrazole-5-carboxylic acid (CAS 1291177-22-4)
- (1s,2r)-1-Amino-2-(trifluoromethyl)cyclopropane-1-carboxylic acid hydrochloride (CAS 1955473-52-5)
- 7-methylthieno[3,2-d]pyrimidine-4-carboxylic acid (CAS 2059987-21-0)
- 5-(tert-Butyl)-3-(4-nitrophenyl)-1,2,4-oxadiazole (CAS 1004398-32-6)
- N-(3-Amino-2,4-difluorophenyl)-2-methylpropane-1-sulfonamide (CAS 1269421-10-4)
- Gastric Inhibitory Polypeptide (human) (CAS 100040-31-1)
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