Progesterone EP Impurity M (17-alpha-Progesterone) CAS 2000-66-0
| CAS No. | 2000-66-0 |
| Molecular Formula | C21H30O2 |
| Molecular Weight | 314.46 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Progesterone EP Impurity M (17-alpha-Progesterone) (C21H30O2) contains a steroid core, a hydroxyl group, an ether linkage. Its high carbon-to-hydrogen ratio confers good lipid solubility, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
Progesterone EP Impurity M (17-alpha-Progesterone) (CAS 2000-66-0) is a certified pharmaceutical impurity reference standard with the molecular formula C21H30O2 and a molecular weight of 314.46 g/mol.
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
As a certified reference material (CRM), Progesterone EP Impurity M (17-alpha-Progesterone) meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C21H30O2 |
| Molecular Weight | 314.46 g/mol |
| Appearance | Off-white to pale yellow crystalline powder |
| Purity | >95% |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 7.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1957 |
Related Progesterone Standards
- Progesterone Impurity 26 (CAS 13611-97-7)
- Progesterone (CAS 57-83-0)
- Progesterone Impurity 57 (CAS 20283-95-8)
- 16-delta Progesterone (CAS 1096-38-4)
- Progesterone EP Impurity A (CAS 24377-08-0)
- Progesterone EP Impurity J (CAS 1162-54-5)
- Progesterone EP Impurity K (CAS 17652-16-3)
- Progesterone EP Impurity H (CAS 1162-56-7)
Recommended Standards
- 3-n-Propyl ether-17α-estradiol (CAS CATO-C4X-163615)
- Rocuronium Impurity 51 (CAS 103088-58-0)
- 5-alfa-Dihydrolevonorgestrel (CAS 78088-19-4)
- Rocuronium Impurity 12 (CAS 50588-42-6)
- Nintedanib Impurity 39 (CAS 3395-81-1)
- Dabrafenib Impurity 28 (CAS CATO-C4X-303328)
- Salbutamol Impurity 210 (CAS CATO-C4X-1176210)
- Methyl (Phenyl 5-Acetamido-4,7,8-tri-O-acetyl-9-azido-3,5,9-trideoxy-2-thio-D-glycero-β-D-galacto-2-nonulopyranosid)onate (CAS 219814-65-0)
- Dibenzyl Ether (CAS 103-50-4)
- Levofloxacin Impurity 88 (CAS CATO-C4X-137188)
- 3-(5-Methyl-1H-pyrazolo[3,4-b]pyridin-1-yl)propanenitrile (CAS 1160246-32-1)
- trans-Octahydro-2h-pyrido[1,2-a]pyrazine-7-methanol (CAS 145012-50-6)
- 3,3-Dimethoxycyclohex-1-ene (CAS 1728-18-3)
- Urotensin II-Related Peptide (human, mouse, rat) (CAS 342878-90-4)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com