2,2-Difluoro-2-phenylacetonitrile CAS 2002-72-4
| CAS No. | 2002-72-4 |
| Molecular Formula | C8H5F2N |
| Molecular Weight | 153.13 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
CATO supplies 2,2-Difluoro-2-phenylacetonitrile (CAS 2002-72-4), a certified reference material (molecular formula C8H5F2N, MW 153.13 g/mol) for analytical method development and quality control.
2,2-Difluoro-2-phenylacetonitrile (C8H5F2N) contains a nitrogen-containing heterocyclic scaffold, a nitrile group, fluorine substitution. Halogen substitution raises its density and boiling point; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
As a certified reference material (CRM), 2,2-Difluoro-2-phenylacetonitrile meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C8H5F2N |
| Molecular Weight | 153.13 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 6.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1957 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 1 |
Related Difluoro Standards
- 2,5-Difluoro-4-methylbenzonitrile (CAS 1003708-66-4)
- 3,5-Difluoro-2-methylbenzonitrile (CAS 1003708-74-4)
- 4,5-Difluoro-2-methylbenzonitrile (CAS 1003708-82-4)
- 2,3-Difluoro-5-methylbenzonitrile (CAS 1003712-18-2)
- 2,5-Difluoro-3-methylbenzonitrile (CAS 1003712-20-6)
- 3,5-Difluoro-1H-indole (CAS 1557400-57-3)
- 3,5-Difluoro-4-methylbenzonitrile (CAS 170572-50-6)
- 2,4-Difluoro-6-methylbenzonitrile (CAS 1803782-57-1)
Recommended Standards
- 2-(Difluoromethyl)benzonitrile (CAS 799814-30-5)
- 2,2-Difluoro-N-(2-hydroxyethyl)propanamide (CAS 851728-91-1)
- 2-(3,4-Difluorophenyl)acetonitrile (CAS 658-99-1)
- 2,2-Difluoro-N-methoxy-N-methylpropanamide (CAS 608537-54-8)
- 5-Chloro-7-methyl-1H-indole (CAS 15936-77-3)
- 3-Bromo-2-fluoro-6-methoxyphenol (CAS 1367707-24-1)
- 2-Methyl-2,3,4,5-tetrahydro-1H-benzo[c]azepin-8-amine (CAS 223699-36-3)
- 2-Chloro-n-methylbenzene-1-sulfonamide (CAS 17260-67-2)
- tert-Butyl 4-iodo-1-methyl-7-oxo-6-azabicyclo[3.2.1]octane-6-carboxylate (CAS 1259366-15-8)
- 3-(Bromomethyl)-2-methoxy-6-methylpyridine (CAS 1227594-67-3)
- N'-(Furan-2-ylmethylene)-2-((4-methoxyphenyl)amino)acetohydrazide (CAS 303083-30-9)
- 4-Fluoro-3-(4-methylphenyl)benzoic acid (CAS 1261953-27-8)
- Ethyl (5-amino-3-((methyl(phenyl)amino)methyl)pyrido[3,4-b]pyrazin-7-yl)carbamate (CAS 83269-13-0)
- D-[Phe6]-Semaglutide (CAS CATO-C4X-2226213)
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