N-(4-Hydroxypyridin-2-yl)acetamide CAS 2003194-48-5
| CAS No. | 2003194-48-5 |
| Molecular Formula | C7H8N2O2 |
| Molecular Weight | 152.15 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The molecular framework of N-(4-Hydroxypyridin-2-yl)acetamide (C7H8N2O2) is characterized by an amino-acid-derived structure, an amide group, a hydroxyl group, an ether linkage. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
N-(4-Hydroxypyridin-2-yl)acetamide (CAS 2003194-48-5), molecular formula C7H8N2O2 and molecular weight 152.15 g/mol, is a CATO reference standard with documented purity and traceability.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C7H8N2O2 |
| Molecular Weight | 152.15 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (faint amine-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 5.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1996 |
| Nitrogen Atoms | 2 |
Related N Standards
- N-(4-Hydroxypyridin-3-yl)acetamide (CAS 101860-99-5)
- N-(5-Hydroxypyridin-2-yl)acetamide (CAS 159183-89-8)
- N-(1-hydroxypyridin-2(1H)-ylidene)acetamide (CAS 6994-14-5)
- N-(3-Hydroxypyridin-4-yl)acetamide (CAS 70118-99-9)
- N-(5-Hydroxypyridin-3-yl)acetamide (CAS 78156-36-2)
- N-(6-hydroxypyridin-2-yl)acetamide (CAS 770-20-7)
- N-(6-Hydroxypyridin-3-yl)acetamide (CAS 41292-43-7)
- 2-(5-Hydroxypyridin-3-yl)acetic acid (CAS 100958-68-7)
Recommended Standards
- N-(4H-1,2,4-Triazol-4-yl)cyclopropanecarboxamide (CAS 550299-57-5)
- N-(5-Aminopyrimidin-2-yl)acetamide (CAS 59690-85-6)
- N-(3-Methylisoxazol-5-yl)acrylamide (CAS 303129-82-0)
- N-(5-Cyclopropylisoxazol-3-yl)formamide (CAS 55809-17-1)
- Tert-butyl 8-(hydroxymethyl)-5-azaspiro[2.5]Octane-5-carboxylate (CAS 2411641-73-9)
- 4-(Piperidin-1-yl)butan-1-amine (CAS 74247-30-6)
- 2-(3-Ethoxyphenyl)propan-2-ol (CAS 939983-37-6)
- Methyl 2-(aminomethyl)-3-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)benzoate (CAS 1333319-47-3)
- Xanomeline Impurity 10 (CAS CATO-C4X-330110)
- Iberiotoxin (CAS 129203-60-7)
- N-(5-(3-(Phenylsulfonyl)propanoyl)-4,5,6,7-tetrahydrothiazolo[5,4-c]pyridin-2-yl)furan-3-carboxamide (CAS 1448066-44-1)
- 2-Bromo-5,10-dihydrophenazine (CAS 496269-44-4)
- 4-(Chloromethyl)-N-cyclohexylbenzamide (CAS 864265-14-5)
- Semaglutide impurity 267 (CAS CATO-C4X-2226267)
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