4-Ethynyl-1,4-dihydro-8-methyl-1-[(4-methylphenyl)sulfonyl]-2H-3,1-benzoxazin-2-one CAS 2005451-25-0
| CAS No. | 2005451-25-0 |
| Molecular Formula | C18H15NO4S |
| Molecular Weight | 341.38 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
CATO supplies 4-Ethynyl-1,4-dihydro-8-methyl-1-[(4-methylphenyl)sulfonyl]-2H-3,1-benzoxazin-2-one (CAS 2005451-25-0), a certified reference material (molecular formula C18H15NO4S, MW 341.38 g/mol) for analytical method development and quality control.
The molecular framework of 4-Ethynyl-1,4-dihydro-8-methyl-1-[(4-methylphenyl)sulfonyl]-2H-3,1-benzoxazin-2-one (C18H15NO4S) is characterized by a flavonoid core, an amide group, a sulfone group, a hydroxyl group, an ether linkage. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C18H15NO4S |
| Molecular Weight | 341.38 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 12.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1996 |
| Nitrogen Atoms | 1 |
| Sulfur Atoms | 1 |
Related Ethynyl Standards
- 4-Ethynyl-1,4-dihydro-5-methyl-1-[(4-methylphenyl)sulfonyl]-2H-3,1-benzoxazin-2-one (CAS 2236555-88-5)
- 4-Ethynyl-4-methyl-1-tosyl-1,4-dihydro-2H-benzo[d][1,3]oxazin-2-one (CAS 2210312-81-3)
- 1-Ethynyl-3-methylcyclohexan-1-ol (CAS 24580-53-8)
- [8-ethynyl-7-fluoro-3-(methoxymethoxy)-1-naphthyl] 2,2-dimethylpropanoate (CAS 2621932-44-1)
- Ethynyl Estradiol 17-Acetate (CAS 21221-29-4)
- Ethynyl Estradiol 3-Acetate (CAS 5779-47-5)
- 2-(8-Ethynyl-3-(methoxymethoxy)naphthalen-1-yl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane (CAS 2834759-52-1)
- 4-Ethynyl-6-fluoro-1-tosyl-1,4-dihydro-2H-benzo[d][1,3]oxazin-2-one (CAS 2093115-06-9)
Recommended Standards
- 4-(Naphthalene-2-sulfonamidomethyl)benzoic acid (CAS 208176-29-8)
- 4-Methyl-N-[3-(pyrazin-2-yloxy)phenyl]benzene-1-sulfonamide (CAS 866157-04-2)
- 4-(4-Methoxyphenyl)-N-(2-methyl-4-nitrophenyl)thiazol-2-amine (CAS 685108-64-9)
- 4-Oxo-4-((5-(phenylthio)-1H-benzo[d]imidazol-2-yl)amino)butanoic acid (CAS 574729-96-7)
- Methyl 2,3,4-tri-O-benzyl-6-O-trityl-a-D-mannopyranoside (CAS 40653-13-2)
- 5-chloro-1-(3-ethoxypropyl)-1H-1,3-benzodiazole-2-carbaldehyde (CAS 1437435-52-3)
- 6-Methylbenzo[d][1,2,3]triazin-4(1H)-one (CAS 91532-23-9)
- 4-Amino-1-(2-Deoxy-2-Fluoro-beta-D-Arabinofuranosyl)-5-Ethyl-2(1H)-Pyrimidinone (CAS 95740-17-3)
- 1-[2-(4-nitrophenyl)ethyl]-2,5-dihydro-1h-pyrrole-2,5-dione (CAS 1292476-04-0)
- 1-(2,4-Dimethylthiazol-5-yl)-2-(pyrrolidin-2-yl)ethan-1-one (CAS 1531061-03-6)
- 4-Ethyl-2-nitrophenol (CAS 56520-98-0)
- 4,5-Dichloro-6-(difluoromethyl)pyrimidine (CAS 425394-19-0)
- 1-(Benzyloxy)-2-(bromomethyl)-4-(tert-butyl)benzene (CAS 1956381-45-5)
- Semaglutide impurity 32 (CAS CATO-C4X-222632)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com