2-[4-(4-Chloro-2-fluorophenyl)-1-piperazinyl]aniline CAS 2006277-40-1
| CAS No. | 2006277-40-1 |
| Molecular Formula | C16H17ClFN3 |
| Molecular Weight | 305.78 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
CATO supplies 2-[4-(4-Chloro-2-fluorophenyl)-1-piperazinyl]aniline (CAS 2006277-40-1), a certified reference material (molecular formula C16H17ClFN3, MW 305.78 g/mol) for analytical method development and quality control.
The molecular framework of 2-[4-(4-Chloro-2-fluorophenyl)-1-piperazinyl]aniline (C16H17ClFN3) is characterized by a nitrogen-containing heterocyclic scaffold, a nitrile group, fluorine/chlorine substitution. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C16H17ClFN3 |
| Molecular Weight | 305.78 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 9.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1996 |
| Halogen Content | F/Cl-containing |
| Nitrogen Atoms | 3 |
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Recommended Standards
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- [1,3]Dioxolo[4,5-b]pyridin-6-ylmethanol (CAS 162320-63-0)
- 1-Mesityl-5-oxopyrrolidine-3-carboxylic acid (CAS 63675-25-2)
- Methyl 4-(3-hydroxyphenyl)-1,6-dimethyl-2-oxo-1,2,3,4-tetrahydropyrimidine-5-carboxylate (CAS 301319-88-0)
- Tert-butyl (S)-3-hydroxy-4-methylenepiperidine-1-carboxylate (CAS 1101840-75-8)
- 1-Propylcyclohexanol (CAS 5445-24-9)
- Methyl 3-aminobenzo[b]thiophene-2-carboxylate 1,1-dioxide (CAS 1707586-40-0)
- HPD-OSu [O-Succinimidyl-1,3-dimethylpropyleneuronium Hexafluorophosphate] (CAS 443305-32-6)
- Cyclolinopeptide B (CAS 193139-41-2)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com