3-[(4-Fluorophenyl)[(2-tetrahydropyranyl)oxy]methyl]isoxazole-4-carboxylic Acid CAS 2006277-64-9
| CAS No. | 2006277-64-9 |
| Molecular Formula | C16H16FNO5 |
| Molecular Weight | 321.30 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
CATO supplies 3-[(4-Fluorophenyl)[(2-tetrahydropyranyl)oxy]methyl]isoxazole-4-carboxylic Acid (CAS 2006277-64-9), a certified reference material (molecular formula C16H16FNO5, MW 321.30 g/mol) for analytical method development and quality control.
Owing to a flavonoid core, an amide group, a hydroxyl group, an ether linkage, fluorine substitution, 3-[(4-Fluorophenyl)[(2-tetrahydropyranyl)oxy]methyl]isoxazole-4-carboxylic Acid is typically pale yellow to yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 321.30 g/mol — guide the selection of appropriate sample preparation and analytical techniques. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
As a certified reference material (CRM), 3-[(4-Fluorophenyl)[(2-tetrahydropyranyl)oxy]methyl]isoxazole-4-carboxylic Acid meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C16H16FNO5 |
| Molecular Weight | 321.30 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 9.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1996 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 1 |
Related Fluorophenyl Standards
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- 4-(4-Fluorophenyl)-2-(5-phenyl-1H-pyrazol-1-yl)-1,3-thiazole (CAS 956977-61-0)
- 2-{4-[(4-fluorophenyl)methyl]piperazin-1-yl}-1-(morpholin-4-yl)ethan-1-one (CAS 719286-45-0)
- N1-(3-Fluorophenyl)-N2-((1-isopropylpiperidin-4-yl)methyl)oxalamide (CAS 946382-70-3)
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Recommended Standards
- 2-(Methylthio)-8-nitro-6-(trifluoromethyl)-4H-thiochromen-4-one (CAS 2252473-74-6)
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- 2-(2,4-Dioxo-8-oxa-1,3-diazaspiro[4.5]Decan-3-yl)-N-(3-fluorophenyl)acetamide (CAS 1281077-71-1)
- 5-Acetyl-7-fluoro-4-phenylpyrano[3,2-b]indol-2(5H)-one (CAS 2347639-56-7)
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- 2-(Difluoromethyl)-3-fluoroaniline (CAS 2091605-37-5)
- 5-Chloro-1-isopropyl-1H-pyrazol-4-amine (CAS 1374830-10-0)
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- Semaglutide impurity 75 (CAS CATO-C4X-222675)
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