1-Methyl-5-(trifluoromethyl)pyridin-2(1H)-one CAS 201160-48-7
| CAS No. | 201160-48-7 |
| Molecular Formula | C7H6F3NO |
| Molecular Weight | 177.12 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
As a certified reference material (CRM), 1-Methyl-5-(trifluoromethyl)pyridin-2(1H)-one meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
1-Methyl-5-(trifluoromethyl)pyridin-2(1H)-one (CAS 201160-48-7), molecular formula C7H6F3NO and molecular weight 177.12 g/mol, is a CATO reference standard with documented purity and traceability.
Owing to an amide group, a hydroxyl group, an ether linkage, fluorine substitution, an aromatic ring system, 1-Methyl-5-(trifluoromethyl)pyridin-2(1H)-one is typically off-white to pale yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 177.12 g/mol — guide the selection of appropriate sample preparation and analytical techniques. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C7H6F3NO |
| Molecular Weight | 177.12 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 4.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2014 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 1 |
Related Methyl Standards
- (3-(Trifluoromethyl)pyridin-4-yl)methanol (CAS 1227598-69-7)
- 3-Methyl-5-(trifluoromethyl)pyridin-2(1H)-one (CAS 124432-65-1)
- 4-Methyl-6-trifluoromethyl-pyridin-3-ol 1253790-72-5 4-Methyl-6-(trifluoromethyl)pyridin-3-ol (CAS 1253790-72-5)
- 2-Methyl-6-(trifluoromethyl)pyridin-3-ol (CAS 1256791-52-2)
- 4-Methyl-2-(trifluoromethyl)pyridine 1-oxide (CAS 1259056-79-5)
- 1-Methyl-3-(trifluoromethyl)pyridin-2(1H)-one (CAS 1311829-52-3)
- 3-(Trifluoromethyl)pyridine-2-methanol (CAS 131747-44-9)
- (4-(Trifluoromethyl)pyridin-2-yl)methanol (CAS 131747-46-1)
Recommended Standards
- 1-isocyanato-3-(trifluoromethyl)bicyclo[1.1.1]pentane (CAS 2735701-12-7)
- 2-(Difluoromethoxy)-4-fluoroaniline (CAS 832740-98-4)
- 1,1,1-Trifluoro-4-(prop-2-ynylamino)but-3-en-2-one (CAS 215657-65-1)
- 2-(Hydroxymethyl)-5-(trifluoromethyl)pyridine (CAS 31181-84-7)
- 7-Amino-1,3-naphthalenedisulfonic acid (CAS 86-65-7)
- (1S,2R)-2-[(1,2-O-Isopropylidene)dihydroxyethyl]-6-fluorochroman-4-one (CAS 797054-21-8)
- 3-(bromomethyl)-3-(propan-2-yloxy)oxolane (CAS 1935287-78-7)
- 4-(5-((3,4-Dichlorobenzyl)thio)-4-ethyl-4H-1,2,4-triazol-3-yl)-2-phenylthiazole (CAS 338759-70-9)
- 6-Cyclopropyl-3H-purin-2-amine (CAS 948551-49-3)
- Methyl 4-((tert-butoxycarbonyl)amino)-3-hydroxycyclopent-1-ene-1-carboxylate (CAS 1824432-78-1)
- 1'-(Tert-butoxycarbonyl)-2H-spiro[benzofuran-3,4'-piperidine]-2-carboxylic acid (CAS 937254-18-7)
- Methyl 2-(2-bromo-6-chloropyridin-3-yl)acetate (CAS 1807123-10-9)
- 4-Chloropyrazolo[1,5-a]pyridine-7-carbonitrile (CAS 1268520-74-6)
- Tau Peptide (45-73) (Exon 2/Insert 1 Domain) trifluoroacetate salt (CAS 2022956-54-1)
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