2,4-Dichloro-7,8-dihydro-[1,4]dioxino[2,3-g]quinazoline CAS 20197-82-4
| CAS No. | 20197-82-4 |
| Molecular Formula | C10H6Cl2N2O2 |
| Molecular Weight | 257.07 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
2,4-Dichloro-7,8-dihydro-[1,4]dioxino[2,3-g]quinazoline (CAS 20197-82-4), molecular formula C10H6Cl2N2O2 and molecular weight 257.07 g/mol, is a CATO reference standard with documented purity and traceability.
Structurally, 2,4-Dichloro-7,8-dihydro-[1,4]dioxino[2,3-g]quinazoline (C10H6Cl2N2O2) contains a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, chlorine substitution. The molecule exhibits a degree of unsaturation (DBE) of 8.0, corresponding to approximately 8 ring(s) or double-bond equivalent(s). With a molecular weight of 257.07 g/mol, it falls into the medium-molecular-weight range. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C10H6Cl2N2O2 |
| Molecular Weight | 257.07 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, faint amine-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 8.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1962 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 2 |
Related Dichloro Standards
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Recommended Standards
- 2-(4-Iodophenyl)propanenitrile (CAS 442513-17-9)
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- 2-Bromo-5-(trifluoromethyl)benzenethiol (CAS 60877-19-2)
- 5-(Methoxymethyl)-1,3,4-oxadiazol-2-amine (CAS 302842-60-0)
- 2,2′-(5-Bromo-1,3-phenylene)bis[pyridine] (CAS 150239-89-7)
- tert-Butyl 2-bromo-7-azaspiro[3.5]nonane-7-carboxylate (CAS 1225276-07-2)
- 2,5-Difluoro-4-(methylsulfanyl)phenylboronic acid, pinacol ester (CAS 1383968-47-5)
- 3-Iodopropyl acetate (CAS 62116-24-9)
- 3-Fluoro-4-(propan-2-yloxy)benzaldehyde (CAS 1021231-72-0)
- Formoterol Hemifumarate (CAS CATO-C4X-152543)
- 1-Cyclohexylazetidin-3-amine (CAS 54431-46-8)
- (5-Carbamoylthiophen-3-yl)boronic acid (CAS 957346-67-7)
- Pancreatic Polypeptide (31-36), amide, human (CAS 74012-13-8)
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