Thalidomide-O-amido-C3-NH2 (TFA) CAS 2022182-58-5
| CAS No. | 2022182-58-5 |
| Molecular Formula | C18H20N4O6 |
| Molecular Weight | N/A |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
CATO manufactures Thalidomide-O-amido-C3-NH2 (TFA) under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
CATO supplies Thalidomide-O-amido-C3-NH2 (TFA) (CAS 2022182-58-5), a certified reference material (molecular formula C18H20N4O6C2HF3O2, MW 502.40 g/mol) for analytical method development and quality control.
Owing to a flavonoid core, an amide group, a hydroxyl group, an ether linkage, fluorine substitution, Thalidomide-O-amido-C3-NH2 (TFA) is typically pale yellow to yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 502.40 g/mol — guide the selection of appropriate sample preparation and analytical techniques. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
Physical & Chemical Properties
| Molecular Formula | C18H20N4O6 C2HF3O2 |
| Molecular Weight | 502.40 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 11.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1996 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 4 |
Related Thalidomide Standards
- Thalidomide-propargyl-OH (CAS 1216805-67-2)
- Thalidomide-d4 (CAS 1219177-18-0)
- Thalidomide Impurity 3 (CAS 126663-38-5)
- Thalidomide-5,6-F (CAS 1496997-41-1)
- Thalidomide-O-amido-C4-NH2 (CAS 1799711-24-2)
- Thalidomide-O-amido-C3-PEG3-C1-NH2 (CAS 1799711-29-7)
- Thalidomide-O-amido-C6-NH2 (CAS 1950635-13-8)
- Thalidomide-O-amido-C6-NH2 (TFA) (CAS 1950635-14-9)
Recommended Standards
- 3-([1,1'-Biphenyl]-2-ylamino)-2H-indol-2-one (CAS 21231-48-1)
- 6-tert-Butyl-1-benzothiophene-3-carbonyl chloride (CAS 1160248-92-9)
- 2-Amino-N-(1,3-dimethyl-1H-pyrazol-5-yl)propanamide (CAS 1290828-36-2)
- 1-{3-oxa-6-azatricyclo[6.1.1.0¹,⁶]decan-4-yl}methanamine (CAS 1989672-87-8)
- Cabozantinib 4-Fluorocarbamoyl Methyl Ester Impurity (CAS 1345847-71-3)
- Benzyl 4-{3-[(tert-butoxy)carbonyl]-2-oxo-imidazolidin-1-yl}piperidine-1-carboxylate (CAS 1312118-25-4)
- Gossypetin (CAS 489-35-0)
- Ethyl 4-(ethylamino)piperidine-1-carboxylate (CAS 1021076-03-8)
- 10-Chloro-9-anthraldehyde (CAS 10527-16-9)
- Semaglutide Impurity 16 (CAS CATO-C4X-222616)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com