Tri-tert-butylphosphate CAS 20224-50-4

Purity 97%+In StockPharmaceutical Standards
CAS No.20224-50-4
Molecular FormulaC12H27O4P
Molecular Weight266.31 g/mol
CategoryPharmaceutical Standards / API Standards
AvailabilityIn Stock

Chemical Structure

Tri-tert-butylphosphate CAS 20224-50-4 chemical structure

Description

CATO supplies Tri-tert-butylphosphate (CAS 20224-50-4), a certified reference material (molecular formula C12H27O4P, MW 266.31 g/mol) for analytical method development and quality control.

The molecular framework of Tri-tert-butylphosphate (C12H27O4P) is characterized by a phosphate ester group, a carboxylic acid group, a hydroxyl group, an ether linkage. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.

This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.

As a certified reference material (CRM), Tri-tert-butylphosphate meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.

Physical & Chemical Properties

Molecular FormulaC12H27O4P
Molecular Weight266.31 g/mol
Purity97%+
StorageStore in a cool place (≤25°C), keep sealed and dry
Solubility (reference)Soluble in chloroform, dichloromethane, ethyl acetate, DMSO
StabilityHygroscopic; reseal immediately after opening
Degree of Unsaturation (DBE)-0.5
CAS Registry Year (est.)1962

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