1-(2-Bromo-4-methyl-5-(pyridin-4-yl)-1H-pyrrol-3-yl)ethan-1-one CAS 202285-68-5

Purity 97%+In StockPharmaceutical Standards
CAS No.202285-68-5
Molecular FormulaC12H11BrN2O
Molecular Weight279.13 g/mol
CategoryPharmaceutical Standards / API Standards
AvailabilityIn Stock

Chemical Structure

1-(2-Bromo-4-methyl-5-(pyridin-4-yl)-1H-pyrrol-3-yl)ethan-1-one CAS 202285-68-5 chemical structure

Description

This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.

1-(2-Bromo-4-methyl-5-(pyridin-4-yl)-1H-pyrrol-3-yl)ethan-1-one (CAS 202285-68-5) is a high-purity analytical reference standard with the molecular formula C12H11BrN2O and a molecular weight of 279.13 g/mol.

The molecular framework of 1-(2-Bromo-4-methyl-5-(pyridin-4-yl)-1H-pyrrol-3-yl)ethan-1-one (C12H11BrN2O) is characterized by a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, bromine substitution. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.

As a certified reference material (CRM), 1-(2-Bromo-4-methyl-5-(pyridin-4-yl)-1H-pyrrol-3-yl)ethan-1-one meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.

Physical & Chemical Properties

Molecular FormulaC12H11BrN2O
Molecular Weight279.13 g/mol
Purity97%+
StorageStore at 2-8°C, protect from light, keep tightly closed to prevent evaporation
Solubility (reference)Soluble in DMSO, DMF, methanol
StabilityMay oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light
Degree of Unsaturation (DBE)8.0
UV AbsorptionUV-absorbing
Structural FeaturesAromatic ring present
CAS Registry Year (est.)2014
Halogen ContentBr-containing
Nitrogen Atoms2

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