Rel-(1R,3r,5S)-3-(bis(4-fluorophenyl)methoxy)-8-methyl-8-azabicyclo[3.2.1]octane hydrochloride CAS 202646-03-5
| CAS No. | 202646-03-5 |
| Molecular Formula | C21H23F2NO |
| Molecular Weight | N/A |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
CATO supplies Rel-(1R,3r,5S)-3-(bis(4-fluorophenyl)methoxy)-8-methyl-8-azabicyclo[3.2.1]octane hydrochloride (CAS 202646-03-5), a certified reference material (molecular formula C21H23F2NOHCl, MW 379.88 g/mol) for analytical method development and quality control.
Owing to a steroid core, an amide group, a hydroxyl group, an ether linkage, fluorine/chlorine substitution, Rel-(1R,3r,5S)-3-(bis(4-fluorophenyl)methoxy)-8-methyl-8-azabicyclo[3.2.1]octane hydrochloride is typically pale yellow to yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 379.88 g/mol — guide the selection of appropriate sample preparation and analytical techniques. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C21H23F2NO HCl |
| Molecular Weight | 379.88 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 9.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2014 |
| Halogen Content | F/Cl-containing |
| Nitrogen Atoms | 1 |
Recommended Standards
- 5,3’-Dihydroxy-7,4’-dimethoxyflavone (CAS 32174-62-2)
- N-[(4-Fluorophenyl)methyl]-9H-fluorene-9-carboxamide (CAS 866155-69-3)
- 3-Fluoro-4-(methoxymethyl)phenylboronic acid (CAS 1313738-12-3)
- b-D-Fructofuranosyl-a-D-galactopyranoside (CAS 13322-96-8)
- (R)-(5,5-difluoro-1-methylpiperidin-2-yl)methanamine dihydrochloride (CAS 2227198-64-1)
- 3-Chloro-N-(3-cyano-4-methanesulfinylphenyl)benzamide (CAS 320421-59-8)
- 2-Butenedioic acid (2E)-, polymer with 1,3-isobenzofurandione and 1,2-propanediol (CAS 25719-91-9)
- Butyl 2-(((3-chlorophenyl)carbamoyl)oxy)propanoate (CAS 106320-92-7)
- Ethyl 2-{7-chloro-2-oxo-1H,2H,3H,4H,5H-pyrido[2,3-b][1,4]diazepin-4-yl}acetate (CAS 1638604-52-0)
- Insulin Degludec Impurity 9 (CAS CATO-C4X-21579)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
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- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com