(Z)-2-Benzamido-3-(2-chlorophenyl)acrylic acid CAS 20273-54-5

Purity 97%+In StockPharmaceutical Standards
CAS No.20273-54-5
Molecular FormulaC16H12ClNO3
Molecular Weight301.72 g/mol
CategoryPharmaceutical Standards / API Standards
AvailabilityIn Stock

Chemical Structure

(Z)-2-Benzamido-3-(2-chlorophenyl)acrylic acid CAS 20273-54-5 chemical structure

Description

The occurrence of (Z)-2-Benzamido-3-(2-chlorophenyl)acrylic acid is closely related to a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, chlorine substitution in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.

(Z)-2-Benzamido-3-(2-chlorophenyl)acrylic acid (CAS 20273-54-5) is a high-purity analytical reference standard with the molecular formula C16H12ClNO3 and a molecular weight of 301.72 g/mol.

The molecular framework of (Z)-2-Benzamido-3-(2-chlorophenyl)acrylic acid (C16H12ClNO3) is characterized by a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, chlorine substitution. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.

Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.

As a certified reference material (CRM), (Z)-2-Benzamido-3-(2-chlorophenyl)acrylic acid meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.

Physical & Chemical Properties

Molecular FormulaC16H12ClNO3
Molecular Weight301.72 g/mol
AppearancePale yellow to yellow crystalline powder. (slight halide-like odor)
Purity97%+
StorageStore at 2-8°C, protect from light, keep sealed and dry
Solubility (reference)Soluble in chloroform, dichloromethane, ethyl acetate, DMSO
StabilityMay oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions
Degree of Unsaturation (DBE)11.0
UV AbsorptionUV-absorbing
Structural FeaturesAromatic ring present
CAS Registry Year (est.)1962
Halogen ContentCl-containing
Nitrogen Atoms1

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