1-(m-Tolyl)cyclobutanecarboxylic acid CAS 202737-32-4
| CAS No. | 202737-32-4 |
| Molecular Formula | C12H14O2 |
| Molecular Weight | 190.24 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including 1-(m-Tolyl)cyclobutanecarboxylic acid.
1-(m-Tolyl)cyclobutanecarboxylic acid (CAS 202737-32-4), molecular formula C12H14O2 and molecular weight 190.24 g/mol, is a CATO reference standard with documented purity and traceability.
1-(m-Tolyl)cyclobutanecarboxylic acid (C12H14O2) contains a carboxylic acid group, a hydroxyl group, an ether linkage, an aromatic ring system. Its high carbon-to-hydrogen ratio confers good lipid solubility, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
As a certified reference material (CRM), 1-(m-Tolyl)cyclobutanecarboxylic acid meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C12H14O2 |
| Molecular Weight | 190.24 g/mol |
| Appearance | Off-white to pale yellow crystalline powder |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 6.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2014 |
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- (S)-2-Benzylmorpholine (CAS 947687-18-5)
- 7-Bromo-5-nitroisoquinoline (CAS 1368385-65-2)
- Perfluorophenyl formate (CAS 111333-97-2)
- 6-(4-Bromo-2-methylphenyl)-6-oxohexanoic acid (CAS 898767-34-5)
- 2-amino-N-benzyl-4-methyl-N-propylpentanamide hydrochloride (CAS 1423028-12-9)
- 1,4-dibromo-2,5-difluoro-3-iodobenzene (CAS 1806356-49-9)
- Semaglutide impurity 30 (CAS CATO-C4X-222630)
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