4-(chloromethyl)-1-fluoro-2-nitrobenzene CAS 20274-70-8
| CAS No. | 20274-70-8 |
| Molecular Formula | C7H11ClFNO2 |
| Molecular Weight | 195.62 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Compared with other compounds in its class, the molecular weight of 195.62 g/mol gives 4-(chloromethyl)-1-fluoro-2-nitrobenzene distinctive chromatographic separation conditions and mass-spectrometry parameter settings.
4-(chloromethyl)-1-fluoro-2-nitrobenzene (CAS 20274-70-8), molecular formula C7H11ClFNO2 and molecular weight 195.62 g/mol, is a CATO reference standard with documented purity and traceability.
Structurally, 4-(chloromethyl)-1-fluoro-2-nitrobenzene (C7H11ClFNO2) contains an amide group, a carboxylic acid group, a hydroxyl group, an ether linkage, fluorine/chlorine substitution. The molecule exhibits a degree of unsaturation (DBE) of 2.0, corresponding to approximately 2 ring(s) or double-bond equivalent(s). With a molecular weight of 195.62 g/mol, it falls into the medium-molecular-weight range. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
CATO manufactures 4-(chloromethyl)-1-fluoro-2-nitrobenzene under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C7H11ClFNO2 |
| Molecular Weight | 195.62 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 2.0 |
| CAS Registry Year (est.) | 1962 |
| Halogen Content | F/Cl-containing |
| Nitrogen Atoms | 1 |
Related chloromethyl Standards
- 1-(chloromethyl)-2-fluoro-3-nitrobenzene (CAS 1020718-00-6)
- 2-(Chloromethyl)-6-fluoroquinoline (CAS 124050-15-3)
- 8-(Chloromethyl)-5-fluoroquinoline (CAS 1342349-11-4)
- 8-(Chloromethyl)-6-fluoroquinoline (CAS 1343626-64-1)
- 5-(Chloromethyl)furan-2-sulfonamide (CAS 56038-67-6)
- 2-(Chloromethyl)-5-(pyridin-4-yl)-1,3,4-oxadiazole (CAS 113604-00-5)
- 3-[5-(Chloromethyl)-1,2,4-oxadiazol-3-yl]pyridine (CAS 15328-03-7)
- 3-(Chloromethyl)-5-(pyridin-3-yl)-1,2,4-oxadiazole (CAS 926225-49-2)
Recommended Standards
- 3,5-Dimethylisoxazole-4-sulfonyl Chloride (CAS 80466-79-1)
- 5-(2-Chloroallyl)-2-fluorobenzonitrile (CAS 951888-62-3)
- 2-Chloro-7-fluoro-4-methylquinoline (CAS 271241-25-9)
- 2-Chloro-3-(4-cyano-3-fluorophenyl)-1-propene (CAS 951888-53-2)
- 5’-Boc-4’,5’-dihydro-1’H-spiro[cyclopropane-1,6’-pyrrolo[3,4-c]pyrazol]-3’-amine (CAS 946497-95-6)
- 1-(2,2-Difluoroethyl)dihydropyrimidine-2,4(1H,3H)-dione (CAS 1545647-51-5)
- (R)-2-((tert-butoxycarbonyl)amino)-3-(5-methoxy-1H-indol-3-yl)propanoic acid (CAS 114873-19-7)
- (1R)-1-(3-bromo-4-methoxyphenyl)-2,2,2-trifluoroethan-1-ol (CAS 1461689-27-9)
- 1-(5-Chloro-6-fluoropyridin-2-yl)ethan-1-one (CAS 1260665-65-3)
- 7-Methyl-6-oxo-2H,3H,4H,6H-pyrimido[2,1-b][1,3]thiazine-3-carboxylic acid hydrochloride (CAS 2097937-57-8)
- MCPB D6 (ring D3, methyl D3) (CAS CATO-CCPD102080)
- 3,3'-Dichloro-2,2'-bis(methoxymethoxy)-(+-)-1,1'-binaphthalene (CAS 142010-86-4)
- 1-(Benzo[d][1,3]dioxol-5-yl)-5-(4-methoxyphenyl)-1H-1,2,3-triazole-4-carboxylic acid (CAS 1338654-08-2)
- Semaglutide Impurity 139 (CAS CATO-C4X-2226139)
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