1-Cyclopropyl-1,3-dihydro-2H-Benzimidazol-2 CAS 202859-73-2
| CAS No. | 202859-73-2 |
| Molecular Formula | C10H10N2O |
| Molecular Weight | 174.20 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
As a certified reference material (CRM), 1-Cyclopropyl-1,3-dihydro-2H-Benzimidazol-2 meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
1-Cyclopropyl-1,3-dihydro-2H-Benzimidazol-2 (CAS 202859-73-2), molecular formula C10H10N2O and molecular weight 174.20 g/mol, is a CATO reference standard with documented purity and traceability.
The molecular framework of 1-Cyclopropyl-1,3-dihydro-2H-Benzimidazol-2 (C10H10N2O) is characterized by a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
Physical & Chemical Properties
| Molecular Formula | C10H10N2O |
| Molecular Weight | 174.20 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (faint amine-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 7.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2014 |
| Nitrogen Atoms | 2 |
Related Cyclopropyl Standards
- 2-Cyclopropyl-1,3-benzoxazol-5-amine (CAS 1017027-77-8)
- 3-Cyclopropyl-[1,2,4]triazolo[4,3-a]pyridin-6-amine (CAS 1082471-97-3)
- n-Cyclopropyl-1,3-benzoxazol-2-amine (CAS 1125867-14-2)
- 6-Cyclopropyl-1H-pyrazolo[3,4-b]pyridin-3-amine (CAS 1135283-75-8)
- 3-Cyclopropyl-1H-pyrazolo[3,4-b]pyridin-5-amine (CAS 1186608-75-2)
- 4-cyclopropyl-2-hydroxy-6-methylpyridine-3-carbonitrile (CAS 1346575-96-9)
- 6-Cyclopropyl-2-hydroxy-4-methylnicotinonitrile (CAS 1346576-02-0)
- 2-Cyclopropyl-[1,2,4]triazolo[1,5-a]pyridin-6-amine (CAS 1367801-23-7)
Recommended Standards
- 1-benzyl-4,5-dihydro-1H-pyrazol-5-one (CAS 591235-73-3)
- 1-Ethoxyphthalazine (CAS 90915-02-9)
- 1-Benzyl-1H-pyrazol-4-ol (CAS 226989-35-1)
- 1-ethyl-1H-1,3-benzodiazole-6-carbaldehyde (CAS 813449-05-7)
- (S)-Methyl 2-((benzyloxy)amino)-3,3-dimethylbutanoate (CAS 219919-36-5)
- 4-Chloro-1H-pyrazolo[3,4-b]pyridin-3-amine (CAS 1211520-57-8)
- 3-(Aminomethyl)-N-benzyl-N-ethylpyridin-2-amine (CAS 1152523-40-4)
- n-[2-methyl-1-(5-methyl-4h-1,2,4-triazol-3-yl)propyl]benzamide (CAS 1334147-52-2)
- 4-(O-tolyl)butanoic acid (CAS 6943-79-9)
- 2-Bromo-3-chloro-6-(trifluoromethyl)pyridine (CAS 1211521-13-9)
- 2-Methylpyrido[4,3-d][1,3]oxazin-4-one (CAS 3810-23-9)
- N-(3-acetyl-4-methoxyphenyl)acetamide (CAS 51410-09-4)
- 1,1-Bis(iodomethyl)cyclobutane (CAS 65478-57-1)
- Hexapeptide-10 (CAS 146439-94-3)
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