1-Bromo-4,5-difluoro-2-methoxybenzene CAS 202865-58-5
| CAS No. | 202865-58-5 |
| Molecular Formula | C7H5BrF2O |
| Molecular Weight | 223.01 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including 1-Bromo-4,5-difluoro-2-methoxybenzene.
1-Bromo-4,5-difluoro-2-methoxybenzene (CAS 202865-58-5) is a high-purity analytical reference standard with the molecular formula C7H5BrF2O and a molecular weight of 223.01 g/mol.
Based on its molecular formula C7H5BrF2O, 1-Bromo-4,5-difluoro-2-methoxybenzene contains a hydroxyl group, an ether linkage, fluorine/bromine substitution, an aromatic ring system; these features give the compound characteristic absorption bands in UV spectroscopy. The molecular weight of 223.01 g/mol is directly relevant to the identification of the molecular ion in mass spectrometry. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C7H5BrF2O |
| Molecular Weight | 223.01 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at room temperature, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure |
| Degree of Unsaturation (DBE) | 4.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2014 |
| Halogen Content | F/Br-containing |
Related Bromo Standards
- 4-Bromo-2,6-difluoroanisole (CAS 104197-14-0)
- 2-Bromo-1,1,1,3-tetrafluoro-3-methylbutane (CAS 1099598-06-7)
- 3-Bromo-4,5-difluorobenzyl alcohol (CAS 1143502-71-9)
- (3-Bromo-2,5-difluorophenyl)methanol (CAS 1159186-56-7)
- 2-Bromo-1,4-difluoro-3-methoxybenzene (CAS 1208076-11-2)
- (2-Bromo-3,5-difluorophenyl)methanol (CAS 1256081-83-0)
- (4-Bromo-3,5-difluorophenyl)methanol (CAS 1256276-36-4)
- 3-Bromo-2-(difluoromethyl)phenol (CAS 1261477-43-3)
Recommended Standards
- 1-Bromo-4-(difluoromethoxy)benzene (CAS 5905-69-1)
- 2,3-Dichloro-5,6-dihydroxybenzoic acid (CAS 72517-16-9)
- 1-Bromo-3-(difluoromethoxy)benzene (CAS 262587-05-3)
- 2,6-Dichloro-3-methyl-4-nitropyridine 1-oxide (CAS 2092680-13-0)
- (9H-Fluoren-9-yl)methyl (9-aminononyl)carbamate hydrochloride (CAS 1822868-57-4)
- 2-{[(3,4-dichlorophenyl)carbamoyl]amino}-3-phenylpropyl N-(3,4-dichlorophenyl)carbamate (CAS 338963-06-7)
- 3-Bromo-6-methoxypyrazolo[1,5-b]pyridazine (CAS 1246552-73-7)
- (R)-7-Chlorohepta-2,3-dien-5-yn-1-ol (CAS 74660-77-8)
- 1-(Bromomethyl)-6-chloronaphthalene (CAS 1261454-02-7)
- 4'-(4-Hydroxyphenyl)-2,2':6',2''-terpyridine (CAS 89972-79-2)
- 3-Bromo-propionamidine (CAS 885959-29-5)
- 2-[(4-methylcyclohexyl)sulfamoyl]acetic acid (CAS 1042586-01-5)
- 1-(3-Fluoro-benzyl)-3,5-dimethyl-4-(4,4,5,5-tetramethyl-[1,3,2]dioxaborolan-2-yl)-1H-pyrazole (CAS 1450642-70-2)
- Peptide Impurity 70 TFA Salt (CAS CATO-CPTD788570)
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