Ethacridine Impurity C53 CAS 20304-70-5
| CAS No. | 20304-70-5 |
| Molecular Formula | C15H13N3O3 |
| Molecular Weight | 283.28 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Structurally, Ethacridine Impurity C53 (C15H13N3O3) contains a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage. The molecule exhibits a degree of unsaturation (DBE) of 11.0, corresponding to approximately 11 ring(s) or double-bond equivalent(s). With a molecular weight of 283.28 g/mol, it falls into the medium-molecular-weight range. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
As a process- or degradation-related impurity, Ethacridine Impurity C53 (CAS 20304-70-5, C15H13N3O3) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
As a certified reference material (CRM), Ethacridine Impurity C53 meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C15H13N3O3 |
| Molecular Weight | 283.28 g/mol |
| Appearance | Pale yellow to yellow crystalline powder |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 11.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1962 |
| Nitrogen Atoms | 3 |
Related Ethacridine Standards
- Ethacridine Lactate Impurity 35 (CAS CATO-C4X-260935)
- Ethacridine Lactate Impurity 6 (CAS 451460-48-3)
- Ethacridine Lactate Impurity 29 (CAS CATO-C4X-260929)
- Ethacridine Lactate Impurity 7 (CAS CATO-C4X-26097)
- Ethacridine Lactate EP Impurity B (CAS 855939-48-9)
- Ethacridine Lactate Impurity 14 (CAS CATO-C4X-260914)
- Ethacridine Lactate Impurity 34 (CAS CATO-C4X-260934)
- Ethacridine Lactate Impurity 11 (CAS CATO-C4X-260911)
Recommended Standards
- Dimethyl pyrrolo[2,1-a]isoquinoline-1,2-dicarboxylate (CAS 68950-07-2)
- Ethyl 11-oxo-10,11-dihydrodibenzo[b,f][1,4]oxazepine-8-carboxylate (CAS 81679-41-6)
- Dimethyl 9H-Carbazole-3,6-dicarboxylate (CAS 22404-78-0)
- Ethyl 2,4-diethoxy-5-nitrobenzoate (CAS 59036-73-6)
- Ruxolitinib Impurity 2 (CAS 2102675-42-1)
- Brivaracetam impurity 105 (CAS 2413102-60-8)
- Rifampicin EP Impurity B (CAS 125833-03-6)
- tert-Butyl 4-(3-(4-bromophenyl)ureido)piperidine-1-carboxylate, 97% (CAS 1056676-31-3)
- Roxadustat Impurity 20 (CAS 2599284-48-5)
- 3-Hydroxyquinoline-7-carboxylic acid (CAS 219786-48-8)
- 5-(Naphthalen-2-yl)-1-phenyl-1h-pyrazole-3-carboxylic acid (CAS 144252-16-4)
- 2-(Bromomethyl)-4-methoxybenzonitrile (CAS 28970-91-4)
- 1,1,1-Trichloro-5,8,11,14-tetraoxa-1-silapentadecane (CAS 228700-87-6)
- Hexapeptide-9 (CAS 885024-94-2)
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