1-{Imidazo[1,2-a]pyridine-2-carbonyl}piperazine hydrochloride CAS 2034154-84-0
| CAS No. | 2034154-84-0 |
| Molecular Formula | C12H14N4O |
| Molecular Weight | N/A |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including 1-{Imidazo[1,2-a]pyridine-2-carbonyl}piperazine hydrochloride.
1-{Imidazo[1,2-a]pyridine-2-carbonyl}piperazine hydrochloride (CAS 2034154-84-0) is a high-purity analytical reference standard with the molecular formula C12H14N4OHCl and a molecular weight of 266.73 g/mol.
The molecular framework of 1-{Imidazo[1,2-a]pyridine-2-carbonyl}piperazine hydrochloride (C12H14N4OHCl) is characterized by a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, chlorine substitution. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C12H14N4O HCl |
| Molecular Weight | 266.73 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 7.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1996 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 4 |
Related Imidazo Standards
- Imidazo[1,2-a]pyridine-2-carboxylic acid, 3,5-dichloro-, ethyl ester (CAS 1000018-01-8)
- 2-(Imidazo[1,2-a]pyrazin-3-yl)acetic acid (CAS 1000565-73-0)
- Imidazo[1,2-a]pyridin-8-ol hydrochloride (CAS 100592-11-8)
- 3-(Imidazo[1,2-b]pyridazin-6-ylamino)propan-1-ol (CAS 1012344-88-5)
- Imidazo[1,2-a]pyridin-2-ylmethanesulfonyl chloride (CAS 1016724-48-3)
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- N-(Imidazo[1,2-a]pyridin-2-ylmethyl)cyclopropanamine (CAS 1016744-73-2)
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Recommended Standards
- 1-(4-(Aminomethyl)piperidin-1-yl)-2,2,2-trifluoroethan-1-one (CAS 1343274-58-7)
- Thiobis(ethane-2,1-diyl) didodecanoate (CAS 4275-31-4)
- Methyl 6-amino-4-(3-bromophenyl)-5-cyano-2-[({3-cyano-5H,6H,7H,8H,9H-cyclohepta[b]pyridin-2-yl}sulfanyl)methyl]-4H-pyran-3-carboxylate (CAS 354556-65-3)
- 2,5,6-Triaminopyrimidine-4(3H)-thione (CAS 54-19-3)
- 4-Diethylsulfamoyl-benzoic acid (CAS 1213-06-5)
- Trichloromethyl Chloroformate (CAS 503-38-8)
- 2-([1,1'-Biphenyl]-4-yl)-5,6-dihydroimidazo[2,1-b]thiazole hydrobromide (CAS 1049780-58-6)
- (R)-3-Amino-4-(3-fluorophenyl)butanoic acid hydrochloride (CAS 331763-65-6)
- 3-Benzylquinazoline-2,4(1H,3H)-dione (CAS 1932-42-9)
- Boc-Cholecystokinin Octapeptide (desulfated) (A-1295.0001) (CAS 25687-34-7)
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