5α-Pregnan-3α-ol-20-one-17α,21,21,21-d4 CAS 203805-85-0

Purity 97%+In StockPharmaceutical Standards
CAS No.203805-85-0
Molecular Formula-
Molecular Weight322.52 g/mol
CategoryPharmaceutical Standards / API Standards
AvailabilityIn Stock

Chemical Structure

5α-Pregnan-3α-ol-20-one-17α,21,21,21-d4 CAS 203805-85-0 chemical structure

Description

The occurrence of 5α-Pregnan-3α-ol-20-one-17α,21,21,21-d4 is closely related to deuterium isotope labeling, a steroid core, a hydroxyl group, an ether linkage in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.

5α-Pregnan-3α-ol-20-one-17α,21,21,21-d4 (CAS 203805-85-0) is a high-purity analytical reference standard with the molecular formula C21H30D4O2 and a molecular weight of 322.52 g/mol.

5α-Pregnan-3α-ol-20-one-17α,21,21,21-d4 (C21H30D4O2) contains deuterium isotope labeling, a steroid core, a hydroxyl group, an ether linkage. Its high carbon-to-hydrogen ratio confers good lipid solubility, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).

This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.

The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.

Physical & Chemical Properties

Molecular FormulaC21H30D4O2
Molecular Weight322.52 g/mol
AppearanceOff-white to pale yellow crystalline powder
Purity97%+
StorageStore at 2-8°C, protect from light
Solubility (reference)Soluble in chloroform, dichloromethane, ethyl acetate, DMSO
StabilityMay oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light
Degree of Unsaturation (DBE)7.0
UV AbsorptionUV-absorbing
Structural FeaturesAromatic ring present
CAS Registry Year (est.)2015

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