N-Fmoc-3-(Cbz-amino)-L-alanine CAS 204316-36-9
| CAS No. | 204316-36-9 |
| Molecular Formula | C26H24N2O6 |
| Molecular Weight | 460.48 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including N-Fmoc-3-(Cbz-amino)-L-alanine.
N-Fmoc-3-(Cbz-amino)-L-alanine (CAS 204316-36-9) is a high-purity analytical reference standard with the molecular formula C26H24N2O6 and a molecular weight of 460.48 g/mol.
The molecular framework of N-Fmoc-3-(Cbz-amino)-L-alanine (C26H24N2O6) is characterized by a steroid core, an amide group, a hydroxyl group, an ether linkage. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
As a certified reference material (CRM), N-Fmoc-3-(Cbz-amino)-L-alanine meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C26H24N2O6 |
| Molecular Weight | 460.48 g/mol |
| Appearance | Pale yellow to yellow crystalline powder |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 16.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2015 |
| Nitrogen Atoms | 2 |
Related N Standards
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- N-Fmoc-5,5,5,5,5,5-Hexafluoro-L-leucine (CAS 918667-71-7)
- Fmoc-Tyr-OtBu (CAS 133852-23-0)
- (S)-Fmoc-Meta-Tyrosine O-Tert-Butyl Ether (CAS 204384-71-4)
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Recommended Standards
- N-[(9H-Fluoren-9-ylmethoxy)carbonyl]-3-[[(phenylmethoxy)carbonyl]amino]-D-alanine (CAS 387824-80-8)
- Z-D-Gln(xan)-oh (CAS 327981-02-2)
- N,N'-((1,3,4-Oxadiazole-2,5-diyl)bis(4,1-phenylene))dibenzamide (CAS 92135-07-4)
- Tadalafil Impurity 110 (CAS CATO-C4X-1087110)
- 4-Aminocarbonyl-2-thienylBoronic acid pinacol ester (CAS 1321901-45-4)
- 6-(Trimethylsilyl)-2,3-dihydroindolizine-5(1H)-thione (CAS 113885-17-9)
- 2-(3,5-Dimethyl-1H-pyrazol-1-yl)-N-methylaniline (CAS 1572047-08-5)
- 1-pyrazin-2-ylcyclopropanecarbonitrile (CAS 1159734-50-5)
- 2,7-Bis(2-(dimethylamino)ethoxy)-9H-fluoren-9-one dihydrochloride (CAS 28712-30-3)
- 4-Benzyloxybenzonitrile (CAS 52805-36-4)
- 3-(methylamino)-1-(2,2,2-trifluoroethyl)pyrrolidin-2-one (CAS 1247519-63-6)
- Tert-butyl 2-((3-aminopropyl)thio)acetate (CAS 1477657-39-8)
- N-(3,5-bis(trifluoromethyl)benzyl)-7,9-dimethyl-N-(2-methyl-2H-tetrazol-5-yl)-2,3,4,5-tetrahydro-1H-benzo[b]azepin-5-amine (CAS 1539285-92-1)
- Semaglutide Impurity 128 (CAS 2490269-78-6)
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