1,2,3,4-tetrahydroisoquinoline-4-carboxamide hydrochloride CAS 2044837-92-3
| CAS No. | 2044837-92-3 |
| Molecular Formula | C10H12N2O |
| Molecular Weight | N/A |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The molecular framework of 1,2,3,4-tetrahydroisoquinoline-4-carboxamide hydrochloride (C10H12N2OHCl) is characterized by a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, chlorine substitution. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
CATO supplies 1,2,3,4-tetrahydroisoquinoline-4-carboxamide hydrochloride (CAS 2044837-92-3), a certified reference material (molecular formula C10H12N2OHCl, MW 212.68 g/mol) for analytical method development and quality control.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
As a certified reference material (CRM), 1,2,3,4-tetrahydroisoquinoline-4-carboxamide hydrochloride meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C10H12N2O HCl |
| Molecular Weight | 212.68 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 5.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1997 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 2 |
Related tetrahydroisoquinoline Standards
- 1-Methyl-5-(1,2,3,4-tetrahydroisoquinoline-2-carbonyl)-1H-pyrazole-4-carboxylic acid (CAS 1006455-90-8)
- 1-oxo-1,2,3,4-tetrahydroisoquinoline-4-carboxylic acid (CAS 101301-17-1)
- 7-Ethyl-1,2,3,4-tetrahydroisoquinoline (CAS 1017125-75-5)
- 2-[(1,2,3,4-tetrahydroisoquinoline-2-carbonyl)amino]acetic acid (CAS 1018299-34-7)
- 5,6,7,8-Tetrahydroisoquinoline-4-carboxylic acid (CAS 1019111-31-9)
- 3-(1,2,3,4-Tetrahydroisoquinoline-2-carbonyl)phenol (CAS 1019438-49-3)
- 2-Ethyl-1,2,3,4-tetrahydroisoquinoline-3-carboxylic acid (CAS 1022919-86-3)
- Methyl 1,2,3,4-tetrahydroisoquinoline-8-carboxylate (CAS 1028330-54-2)
Recommended Standards
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- Methyl 5-(3,4-Dimethoxyphenyl)isoxazole-3-carboxylate (CAS 517870-17-6)
- 2-(Pyrazin-2-yl)ethan-1-amine oxalate (CAS 1955557-80-8)
- (4-Ethylthiophen-3-yl)(phenyl)methanol (CAS 1248927-64-1)
- Methyl 2-(2-(N-methylmethylsulfonamido)acetamido)thiophene-3-carboxylate (CAS 1171781-23-9)
- (1A'R,2a'R,6'S,6a'S,7'S,7a'R)-6',7'-dihydroxy-1a',7a'-dihydro-7'H-spiro[naphtho[1,8-de][1,3]dioxine-2,2'-[2a,6a]epoxynaphtho[2,3-b]oxiren]-3'(6'H)-one (CAS 152607-03-9)
- (2α,5α)-2-Methylandrostane-3,17-dione (CAS 5470-27-9)
- Methoxy(propan-2-yl)amine (CAS 32118-22-2)
- Semaglutide impurity 46 (CAS CATO-C4X-222646)
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