3-Chloro-N-(4-phenyl-1,3-thiazol-2-yl)propanamide CAS 20495-98-1

Purity 97%+In StockPharmaceutical Standards
CAS No.20495-98-1
Molecular FormulaC12H11ClN2OS
Molecular Weight266.75 g/mol
CategoryPharmaceutical Standards / API Standards
AvailabilityIn Stock

Chemical Structure

3-Chloro-N-(4-phenyl-1,3-thiazol-2-yl)propanamide CAS 20495-98-1 chemical structure

Description

CATO supplies 3-Chloro-N-(4-phenyl-1,3-thiazol-2-yl)propanamide (CAS 20495-98-1), a certified reference material (molecular formula C12H11ClN2OS, MW 266.75 g/mol) for analytical method development and quality control.

The molecular framework of 3-Chloro-N-(4-phenyl-1,3-thiazol-2-yl)propanamide (C12H11ClN2OS) is characterized by a nitrogen-containing heterocyclic scaffold, an amide group, sulfur-containing functionality, a hydroxyl group, an ether linkage, chlorine substitution. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).

This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.

As a certified reference material (CRM), 3-Chloro-N-(4-phenyl-1,3-thiazol-2-yl)propanamide meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.

Physical & Chemical Properties

Molecular FormulaC12H11ClN2OS
Molecular Weight266.75 g/mol
Purity97%+
StorageStore at 2-8°C, protect from light, keep tightly closed to prevent evaporation
Solubility (reference)Soluble in DMSO, DMF, methanol
StabilityMay oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light
Degree of Unsaturation (DBE)8.0
UV AbsorptionUV-absorbing
Structural FeaturesAromatic ring present
CAS Registry Year (est.)1962
Halogen ContentCl-containing
Nitrogen Atoms2
Sulfur Atoms1

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