Oxymetazoline Impurity 3 HCl CAS 205035-03-6
| CAS No. | 205035-03-6 |
| Molecular Formula | C16H22N2O |
| Molecular Weight | N/A |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
As a process- or degradation-related impurity, Oxymetazoline Impurity 3 HCl (CAS 205035-03-6, C16H22N2OHCl) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.
Structurally, Oxymetazoline Impurity 3 HCl (C16H22N2OHCl) contains a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, chlorine substitution. The molecule exhibits a degree of unsaturation (DBE) of 6.0, corresponding to approximately 6 ring(s) or double-bond equivalent(s). With a molecular weight of 294.82 g/mol, it falls into the medium-molecular-weight range. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
CATO manufactures Oxymetazoline Impurity 3 HCl under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C16H22N2O HCl |
| Molecular Weight | 294.82 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor) |
| Purity | >95% |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 6.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2015 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 2 |
Related Oxymetazoline Standards
- Oxymetazoline EP Impurity B HCl (CAS 1218-35-5)
- Oxymetazoline-d4 (imidazoline-d4) (CAS 1262053-60-0)
- Oxymetazoline EP Impurity A HCl (CAS 1391053-50-1)
- Oxymetazoline EP Impurity A (CAS 1391194-44-7)
- Oxymetazoline (CAS 1491-59-4)
- Oxymetazoline Impurity 19 (CAS 1895424-66-4)
- Oxymetazoline Impurity 3 (CAS 227953-47-1)
- Oxymetazoline Hydrochloride (CAS 2315-02-8)
Recommended Standards
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- Bosutinib Impurity 38 (CAS CATO-C4X-184738)
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- Atorvastatin Impurity 69 (CAS CATO-C4X-113269)
- Tert-butyl (2R,4S)-4-amino-2-(methoxymethyl)pyrrolidine-1-carboxylate (CAS 1932561-50-6)
- Citalopram Hydrochloride (CAS 85118-27-0)
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- P-tolyl methanesulfonate (CAS 17177-63-8)
- 2,6-Diaza-spiro[3.4]octan-5-one tosylate (CAS 2305079-56-3)
- Osteoblast-Adhesive Peptide (CAS 193613-75-1)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com