1-(2-((5-Amino-4-((2-(dimethylamino)ethyl)(methyl)amino)-2-methoxyphenyl)amino)pyrimidin-4-yl)-5-fluoro-3-methyl-1,3-dihydro-2H-benzo[d]imidazol-2-one CAS 2050908-12-6
| CAS No. | 2050908-12-6 |
| Molecular Formula | C24H29FN8O2 |
| Molecular Weight | 480.54 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including 1-(2-((5-Amino-4-((2-(dimethylamino)ethyl)(methyl)amino)-2-methoxyphenyl)amino)pyrimidin-4-yl)-5-fluoro-3-methyl-1,3-dihydro-2H-benzo[d]imidazol-2-one.
1-(2-((5-Amino-4-((2-(dimethylamino)ethyl)(methyl)amino)-2-methoxyphenyl)amino)pyrimidin-4-yl)-5-fluoro-3-methyl-1,3-dihydro-2H-benzo[d]imidazol-2-one (CAS 2050908-12-6), molecular formula C24H29FN8O2 and molecular weight 480.54 g/mol, is a CATO reference standard with documented purity and traceability.
The molecular framework of 1-(2-((5-Amino-4-((2-(dimethylamino)ethyl)(methyl)amino)-2-methoxyphenyl)amino)pyrimidin-4-yl)-5-fluoro-3-methyl-1,3-dihydro-2H-benzo[d]imidazol-2-one (C24H29FN8O2) is characterized by a steroid core, an amide group, a hydroxyl group, an ether linkage, fluorine substitution. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C24H29FN8O2 |
| Molecular Weight | 480.54 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor) |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 14.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1997 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 8 |
Related Amino Standards
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Recommended Standards
- Rosuvastatin Impurity 222 (CAS CATO-C4X-1169222)
- 1-(4-((6,7-Dimethoxyquinolin-4-yl)oxy)-2-methoxyphenyl)-3-(1-(thiazol-2-yl)ethyl)urea (CAS 623142-96-1)
- N-tert-Butyloxycarbonylamino KU-0058948 (CAS 874116-49-1)
- 1-(P-tolyl)-2-(4-(p-tolyl)-2-((4-(trifluoromethyl)benzyl)thio)-1H-imidazol-1-yl)ethan-1-one (CAS 685107-60-2)
- (Trp63,Trp64)-C3a (63-77) (H-1264.0005) (CAS 130154-64-2)
- 4-(Allylamino)-2,6-diphenylpyrimidine-5-carbonitrile (CAS 320418-31-3)
- 4-Cyano-6-iodopicolinic acid (CAS 1393584-11-6)
- 1-(2-Amino-4-oxo-1,4,5,6,7,8-hexahydropteridin-6-yl)propane-1,2-dione (CAS 89687-39-8)
- N-(2-Chloro-6-methylphenyl)-3-(pyrrolidin-1-yl)butanamide hydrochloride (CAS 77985-19-4)
- Lornoxicam Impurity 78 (CAS 16817-89-3)
- 2-(5-Amino-2-methoxyphenyl)-1lambda6,2-thiazolidine-1,1-dione (CAS 927995-95-7)
- 1-(2-Bromo-6-fluorophenyl)-N-methylmethanamine (CAS 1287218-39-6)
- 1-(2,5-Difluorophenyl)cyclopropan-1-amine hydrochloride (CAS 1269397-45-6)
- Dendroaspis Natriuretic Peptide (CAS 255721-52-9)
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