2-(4,5-Dihydro-1H-imidazol-2-yl)quinoline hydrochloride CAS 205437-64-5
| CAS No. | 205437-64-5 |
| Molecular Formula | C12H11N3 |
| Molecular Weight | N/A |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including 2-(4,5-Dihydro-1H-imidazol-2-yl)quinoline hydrochloride.
2-(4,5-Dihydro-1H-imidazol-2-yl)quinoline hydrochloride (CAS 205437-64-5), molecular formula C12H11N3HCl and molecular weight 233.70 g/mol, is a CATO reference standard with documented purity and traceability.
The molecular framework of 2-(4,5-Dihydro-1H-imidazol-2-yl)quinoline hydrochloride (C12H11N3HCl) is characterized by a nitrogen-containing heterocyclic scaffold, a nitrile group, chlorine substitution. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
As a certified reference material (CRM), 2-(4,5-Dihydro-1H-imidazol-2-yl)quinoline hydrochloride meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C12H11N3 HCl |
| Molecular Weight | 233.70 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 8.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2015 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 3 |
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Recommended Standards
- 3,3-Dichloro-2-(phosphonomethyl)acrylic acid (CAS 122279-84-9)
- N-((3R,4R,5S,6R)-2,4,5-trihydroxy-6-((((2R,3R,4S,5R,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-2-yl)oxy)methyl)tetrahydro-2H-pyran-3-yl)acetamide (CAS 50787-10-5)
- 2-((4-Chlorophenyl)amino)pyrimidin-4(1H)-one (CAS 158661-61-1)
- Methyl 5,6-dichloro-2-methylpyridine-3-carboxylate (CAS 1039037-66-5)
- Methyltri-n-octylammonium Bis(trifluoromethanesulfonyl)imide (CAS 375395-33-8)
- (S)-tert-Butyl 2-((1R,2S)-1-hydroxy-2-methylbut-3-en-1-yl)pyrrolidine-1-carboxylate (CAS 159173-40-7)
- 3-Methyl-5-oxo-2,5-dihydro-1H-pyrazole-1-carbothioamide (CAS 35290-52-9)
- 3-Pyrrolidin-2-yl-indole-1-carboxylic acid tert-butyl ester (CAS 885272-31-1)
- Lercanidipine Impurity 56 (CAS CATO-C4X-136456)
- Tirzepatide Impurity 18 (CAS CATO-C4X-324018)
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