Cabozantinib Impurity 25 CAS 205448-31-3
| CAS No. | 205448-31-3 |
| Molecular Formula | C10H8ClNO2 |
| Molecular Weight | 209.63 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including Cabozantinib Impurity 25.
Cabozantinib Impurity 25 (CAS 205448-31-3) is a high-purity analytical reference standard with the molecular formula C10H8ClNO2 and a molecular weight of 209.63 g/mol.
Cabozantinib Impurity 25 (C10H8ClNO2) contains a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, chlorine substitution. Halogen substitution raises its density and boiling point, its high carbon-to-hydrogen ratio confers good lipid solubility, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
CATO manufactures Cabozantinib Impurity 25 under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C10H8ClNO2 |
| Molecular Weight | 209.63 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 7.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2015 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 1 |
Related Cabozantinib Standards
- Cabozantinib Impurity 16 (CAS 95932-39-1)
- Cabozantinib Impurity 2 (CAS 918642-61-2)
- Cabozantinib Impurity 12 (CAS 145591-80-6)
- Cabozantinib Impurity 27 (CAS 332-07-0)
- Cabozantinib Impurity 30 (CAS 261783-72-6)
- Cabozantinib Impurity 24 (CAS CATO-C4X-201824)
- Cabozantinib Impurity 39 (CAS CATO-C4X-201839)
- Cabozantinib Impurity 41 (CAS 2105956-20-3)
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Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com