4-(3-fluorophenyl)-2-(piperidin-4-yl)pyrimidine hydrochloride CAS 2059949-59-4
| CAS No. | 2059949-59-4 |
| Molecular Formula | C15H16FN3 |
| Molecular Weight | N/A |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
As a certified reference material (CRM), 4-(3-fluorophenyl)-2-(piperidin-4-yl)pyrimidine hydrochloride meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
4-(3-fluorophenyl)-2-(piperidin-4-yl)pyrimidine hydrochloride (CAS 2059949-59-4), molecular formula C15H16FN3HCl and molecular weight 293.77 g/mol, is a CATO reference standard with documented purity and traceability.
The molecular framework of 4-(3-fluorophenyl)-2-(piperidin-4-yl)pyrimidine hydrochloride (C15H16FN3HCl) is characterized by a nitrogen-containing heterocyclic scaffold, a nitrile group, fluorine/chlorine substitution. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
Physical & Chemical Properties
| Molecular Formula | C15H16FN3 HCl |
| Molecular Weight | 293.77 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 8.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1997 |
| Halogen Content | F/Cl-containing |
| Nitrogen Atoms | 3 |
Related fluorophenyl Standards
- 3-[(3-fluorophenyl)methyl]pyrrolidine (CAS 1000198-80-0)
- 3-(3-Fluorophenyl)-3-oxopropanoic acid (CAS 1000530-96-0)
- Ethyl 1-(4-fluorophenyl)-5-oxo-2,5-dihydro-1H-1,2,4-triazole-3-carboxylate (CAS 1000573-68-1)
- 1000574-26-4 2-(4-Fluorophenyl)-6-methylthio-4H-thiopyran-4-one MFCD09877819 (CAS 1000574-26-4)
- Ethyl 1-(2-fluorophenyl)-5-oxo-2,5-dihydro-1H-1,2,4-triazole-3-carboxylate (CAS 1000575-18-7)
- 100074-04-2 5-(4-Fluorophenyl)-1-pentene MFCD11553774 (CAS 100074-04-2)
- 3-(2-Fluorophenyl)-4-hydroxyfuran-2(5H)-one (CAS 100074-44-0)
- N-[2-(4-fluorophenyl)ethyl]-1H-imidazole-1-carboxamide (CAS 1000931-75-8)
Recommended Standards
- 3-((1H-pyrazol-1-yl)methyl)benzoic acid (CAS 562803-68-3)
- Aluminum trihexadecan-1-olate (CAS 19141-82-3)
- (2R,5R)-Hexane-2,5-diylbis(diphenylphosphine) (CAS 142494-67-5)
- 2-(Difluoromethyl)-5-iodo-4-(trifluoromethoxy)pyridine-3-carboxylic acid (CAS 1804438-90-1)
- 2-(Hydroxymethyl)-1,3-dioxolan-4-yl acetate (CAS 1823616-89-2)
- 4-Hydroxy-6-methyl-5-nitropyridin-2(1H)-one (CAS 88499-61-0)
- 1-Methylcyclopentanecarboxylic Acid (CAS 5217-05-0)
- 5-Chloro-2-(trifluoromethyl)pyridin-4-ol (CAS 1196157-49-9)
- 4-((4-Fluorophenyl)sulfonyl)butan-1-amine (CAS 1018522-55-8)
- Galanin (1-13)-Neuropeptide Y (25-36) amide (CAS 147138-51-0)
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