4-[2-(Difluoromethyl)-1,3-thiazol-5-yl]benzaldehyde CAS 2059955-81-4

Purity 97%+In StockPharmaceutical Standards
CAS No.2059955-81-4
Molecular FormulaC11H7F2NOS
Molecular Weight239.24 g/mol
CategoryPharmaceutical Standards / API Standards
AvailabilityIn Stock

Chemical Structure

4-[2-(Difluoromethyl)-1,3-thiazol-5-yl]benzaldehyde CAS 2059955-81-4 chemical structure

Description

The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.

4-[2-(Difluoromethyl)-1,3-thiazol-5-yl]benzaldehyde (CAS 2059955-81-4) is a high-purity analytical reference standard with the molecular formula C11H7F2NOS and a molecular weight of 239.24 g/mol.

The molecular framework of 4-[2-(Difluoromethyl)-1,3-thiazol-5-yl]benzaldehyde (C11H7F2NOS) is characterized by a nitrogen-containing heterocyclic scaffold, an amide group, sulfur-containing functionality, a hydroxyl group, an ether linkage, fluorine substitution. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.

This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.

Physical & Chemical Properties

Molecular FormulaC11H7F2NOS
Molecular Weight239.24 g/mol
Purity97%+
StorageStore at 2-8°C, protect from light, keep tightly closed to prevent evaporation
Solubility (reference)Soluble in chloroform, dichloromethane, ethyl acetate, DMSO
StabilityMay oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light
Degree of Unsaturation (DBE)8.0
UV AbsorptionUV-absorbing
Structural FeaturesAromatic ring present
CAS Registry Year (est.)1997
Halogen ContentF-containing
Nitrogen Atoms1
Sulfur Atoms1

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