2,2,4-trimethylpiperidine hydrochloride CAS 2060043-37-8
| CAS No. | 2060043-37-8 |
| Molecular Formula | C8H17N |
| Molecular Weight | N/A |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The occurrence of 2,2,4-trimethylpiperidine hydrochloride is closely related to chlorine substitution in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.
2,2,4-trimethylpiperidine hydrochloride (CAS 2060043-37-8) is a high-purity analytical reference standard with the molecular formula C8H17NHCl and a molecular weight of 163.69 g/mol.
The molecular framework of 2,2,4-trimethylpiperidine hydrochloride (C8H17NHCl) is characterized by chlorine substitution. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
CATO manufactures 2,2,4-trimethylpiperidine hydrochloride under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C8H17N HCl |
| Molecular Weight | 163.69 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO |
| Stability | Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 0.0 |
| CAS Registry Year (est.) | 1997 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 1 |
Related trimethylpiperidine Standards
- 1,4,4-Trimethylpiperidine (CAS 1003-84-5)
- 2,2,4-Trimethylpiperidine (CAS 101257-71-0)
- 3,3,4-trimethylpiperidine (CAS 1461715-19-4)
- 2,3,5-trimethylpiperidine (CAS 1797118-66-1)
- Ethyl 2,4,6-trimethylpiperidine-3-carboxylate hydrochloride (CAS 2137784-39-3)
- 2,2,6-Trimethylpiperidine hydrochloride (CAS 2138145-63-6)
- 2,4,6-Trimethylpiperidine (CAS 21974-48-1)
- 1,3,5-Trimethylpiperidine (CAS 27644-32-2)
Recommended Standards
- L-Phenylalanine-15N (CAS 29700-34-3)
- 1-(6-Methoxytetrahydro-2H-pyran-2-yl)-1H-benzo[d][1,2,3]triazole (CAS 300679-34-9)
- Quinoxaline-6-carbaldehyde (CAS 130345-50-5)
- (1R,2R)-2-(aminomethyl)cyclohexan-1-amine dihydrochloride (CAS 1212366-42-1)
- 1-((1-Fluorocyclobutyl)methyl)-1H-pyrazol-4-amine (CAS 2839891-88-0)
- 3-(Cyclohexylmethyl)-1-phenylpiperidine (CAS 1402842-05-0)
- (6-Methoxybenzofuran-2-yl)(4-methoxyphenyl)methanone (CAS 75158-60-0)
- Methyl 2-(1-aminocyclobutyl)acetate hydrochloride (CAS 1584148-97-9)
- Ceritinib Impurity 10 (CAS CATO-C4X-1048910)
- Tripeptide-10 citrulline (CAS 960531-53-7)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com